The Endocannabinoid System (ECS) is primarily responsible for maintaining homeostasis, a
balance in internal environment (temperature, mood, and immune system) and energy input …

Abstract N-acylethanolamines (NAEs), including N-palmitoylethanolamine (PEA), N-
oleoylethanolamine (OEA), N-arachidonoylethanolamine (AEA, anandamide), N …

Post-ingestive signals conveying information about the nutritive properties of food are critical
for regulating ingestive behavior. Here, using an auction task concomitant to fMRI scanning …

Abstract Δ 9-Tetrahydrocannabinol (THC) is the main source of the pharmacological effects
caused by the consumption of cannabis, both the marijuana-like action and the medicinal …

Leptin is the primary signal through which the hypothalamus senses nutritional state and
modulates food intake and energy balance. Leptin reduces food intake by upregulating …

Epidemiological studies have documented a reduced prevalence of Alzheimer's disease
among users of nonsteroidal anti-inflammatory drugs (NSAIDs),,,,. It has been proposed that …

The cannabinoid receptor type 1 (CB1) and its endogenous ligands, the endocannabinoids,
are involved in the regulation of food intake. Here we show that the lack of CB1 in mice with …

The active compound in herbal cannabis, Δ9‐tetrahydrocannabinol, exerts all of its known
central effects through the CB1 cannabinoid receptor. Research on cannabinoid …

Endogenous cannabinoids acting at CB1 receptors stimulate appetite, and CB1 antagonists
show promise in the treatment of obesity. CB1–/–mice are resistant to diet-induced obesity …

During the last few years, the endocannabinoid system has emerged as a highly relevant
topic in the scientific community. Many different regulatory actions have been attributed to …