[HTML][HTML] Enterovirus A71 vaccines

ML Li, SR Shih, BS Tolbert, G Brewer - Vaccines, 2021 - mdpi.com
Enterovirus A71 (EV-A71) is a major causative agent of hand, foot, and mouth disease
(HFMD) and herpangina. Moreover, EV-A71 infection can lead to neurological complications …

[HTML][HTML] Antivirals and vaccines for Enterovirus A71

JY Lin, YA Kung, SR Shih - Journal of biomedical science, 2019 - Springer
Abstract Enterovirus A71 (EV-A71) is an important emerging virus posing a threat to children
under five years old. EV-A71 infection in infants or young children can cause hand-foot-and …

[HTML][HTML] From monovalent to multivalent vaccines, the exploration for potential preventive strategies against hand, foot, and mouth disease (HFMD)

X He, M Zhang, C Zhao, P Zheng, X Zhang, J Xu - Virologica Sinica, 2021 - Springer
Hand, foot, and mouth disease (HFMD) recently emerged as a global public threat. The
licensure of inactivated enterovirus A71 (EV-A71) vaccine was the first step in using a …

Does enterovirus 71 urge for effective vaccine control strategies? Challenges and current opinion

SK Swain, A Gadnayak, JN Mohanty… - Reviews in Medical …, 2022 - Wiley Online Library
Abstract Enterovirus 71 (EV71) is an infectious virus affecting all age groups of people
around the world. It is one of the major aetiologic agents for HFMD (hand, foot and mouth …

Genetic engineering strategies for construction of multivalent chimeric VLPs vaccines

X Lei, X Cai, Y Yang - Expert Review of Vaccines, 2020 - Taylor & Francis
Introduction: Over the past two decades, virus-like particles (VLPs) have been developed as
a new generation of vaccines against viral infections. Based on VLPs, chimeric VLPs (chi …

[HTML][HTML] Antibody generation and immunogenicity analysis of EBV gp42 N-terminal region

J Hong, D Wei, Q Wu, L Zhong, K Chen, Y Huang… - Viruses, 2021 - mdpi.com
Epstein–Barr virus (EBV) is the first reported oncogenic virus and infects more than 90% of
adults worldwide. EBV can establish a latent infection in B lymphocytes which is essential for …

[HTML][HTML] A novel vaccine candidate based on chimeric virus-like particle displaying multiple conserved epitope peptides induced neutralizing antibodies against EBV …

X Zhang, B Zhao, M Ding, S Song, Y Kang, Y Yu… - Theranostics, 2020 - ncbi.nlm.nih.gov
Abstract Rationale: Epstein-Barr virus (EBV) is the causative pathogen for infectious
mononucleosis and many kinds of malignancies including several lymphomas such as …

Artificially designed hepatitis B virus core particles composed of multiple epitopes of type A and O foot‐and‐mouth disease virus as a bivalent vaccine candidate

Y Lei, J Shao, F Zhao, Y Li, C Lei, F Ma… - Journal of medical …, 2019 - Wiley Online Library
Recently, many countries, including China, have experienced a series of type A and O foot‐
and‐mouth disease virus (FMDV) epidemics, causing serious economic losses. Although …

Chimeric enterovirus 71 virus-like particle displaying conserved coxsackievirus A16 epitopes elicits potent immune responses and protects mice against lethal EV71 …

J Luo, C Huo, H Qin, J Hu, L Lei, Z Pan - Vaccine, 2021 - Elsevier
Hand-foot-and-mouth disease (HFMD) is an infectious disease of infants and young children
frequently caused by the enterovirus A species, mainly enterovirus 71 (EV71) and …

[HTML][HTML] A 10-day-old murine model of coxsackievirus A6 infection for the evaluation of vaccines and antiviral drugs

Z Jiang, Y Zhang, H Lin, Q Cheng, X Lu, W Liu… - Frontiers in …, 2021 - frontiersin.org
Coxsackievirus A6 (CVA6) is recognized as a major enterovirus type that can cause severe
hand, foot, and mouth disease and spread widely among children. Vaccines and antiviral …