Linking oxidative stress and DNA damage to changes in the expression of extracellular matrix components
SG Martins, R Zilhão, S Thorsteinsdóttir… - Frontiers in …, 2021 - frontiersin.org
Cells are subjected to endogenous [eg, reactive oxygen species (ROS), replication stress]
and exogenous insults (eg, UV light, ionizing radiation, and certain chemicals), which can …
and exogenous insults (eg, UV light, ionizing radiation, and certain chemicals), which can …
Influence of the co-exposure of microplastics and tetrabromobisphenol A on human gut: Simulation in vitro with human cell Caco-2 and gut microbiota
W Huang, H Yin, Y Yang, L Jin, G Lu, Z Dang - Science of the Total …, 2021 - Elsevier
Microplastics (MPs) pollution becomes an emergent threat to the ecosystem, and its joint
effect with organic contaminants will cause more severe consequences. Recently, MPs has …
effect with organic contaminants will cause more severe consequences. Recently, MPs has …
[HTML][HTML] Caveolin and NOS in the Development of Muscular Dystrophy
M Nakashima, N Suga, S Yoshikawa… - International Journal of …, 2024 - mdpi.com
Caveolin is a structural protein within caveolae that may be involved in transmembrane
molecular transport and/or various intercellular interactions within cells. Specific mutations of …
molecular transport and/or various intercellular interactions within cells. Specific mutations of …
New insights into the size-independent bioactive potential of pristine and UV-B aged polyethylene microplastics
The present study investigates the morphological, physicochemical, and structural changes
occurred by the UV-B aging process of low-density polyethylene microplastics (LDPE MPs) …
occurred by the UV-B aging process of low-density polyethylene microplastics (LDPE MPs) …
Absence of full-length dystrophin impairs normal maturation and contraction of cardiomyocytes derived from human-induced pluripotent stem cells
JM Pioner, X Guan, JM Klaiman… - Cardiovascular …, 2020 - academic.oup.com
Aims Heart failure invariably affects patients with various forms of muscular dystrophy (MD),
but the onset and molecular sequelae of altered structure and function resulting from full …
but the onset and molecular sequelae of altered structure and function resulting from full …
Calcium handling maturation and adaptation to increased substrate stiffness in human iPSC-derived cardiomyocytes: The impact of full-length dystrophin deficiency
JM Pioner, L Santini, C Palandri, M Langione… - Frontiers in …, 2022 - frontiersin.org
Cardiomyocytes differentiated from human induced Pluripotent Stem Cells (hiPSC-CMs) are
a unique source for modelling inherited cardiomyopathies. In particular, the possibility of …
a unique source for modelling inherited cardiomyopathies. In particular, the possibility of …
Both hypoxia-inducible factor 1 and MAPK signaling pathway attenuate PI3K/AKT via suppression of reactive oxygen species in human pluripotent stem cells
P Fojtík, D Beckerová, K Holomková… - Frontiers in Cell and …, 2021 - frontiersin.org
Mild hypoxia (5% O2) as well as FGFR1-induced activation of phosphatidylinositol-4, 5-
bisphosphate 3-kinase/protein kinase B (PI3K/AKT) and MAPK signaling pathways markedly …
bisphosphate 3-kinase/protein kinase B (PI3K/AKT) and MAPK signaling pathways markedly …
DMD Pluripotent Stem Cell Derived Cardiac Cells Recapitulate in vitro Human Cardiac Pathophysiology
S Jelinkova, A Vilotic, J Pribyl, F Aimond… - … in bioengineering and …, 2020 - frontiersin.org
Duchenne muscular dystrophy (DMD) is a severe genetic disorder characterized by the lack
of functional dystrophin. DMD is associated with progressive dilated cardiomyopathy …
of functional dystrophin. DMD is associated with progressive dilated cardiomyopathy …
A. officinarum Hance–P. cablin (Blanco) Benth drug pair improves oxidative stress, intracellular Ca2+ concentrations and apoptosis by inhibiting the AGE/RAGE axis …
X Zheng, Q Xue, Y Wang, L Lu, Y Pan, J Xu… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance Alpinia officinarum Hance is a perennial natural
medicine herbivorous plant, has been used in the management of treat stomach pain and …
medicine herbivorous plant, has been used in the management of treat stomach pain and …
Dystrophin deficiency affects human astrocyte properties and response to damage
In addition to progressive muscular degeneration due to dystrophin mutations, 1/3 of
Duchenne muscular dystrophy (DMD) patients present cognitive deficits. However, there is …
Duchenne muscular dystrophy (DMD) patients present cognitive deficits. However, there is …