Wnt/β-catenin signaling as a driver of hepatocellular carcinoma progression: an emphasis on molecular pathways

M Deldar Abad Paskeh, S Mirzaei… - Journal of …, 2021 - Taylor & Francis
Liver cancers cause a high rate of death worldwide and hepatocellular carcinoma (HCC) is
considered as the most common primary liver cancer. HCC remains a challenging disease …

MicroRNAs and obesity-induced endothelial dysfunction: key paradigms in molecular therapy

K Ait-Aissa, QM Nguyen, M Gabani, A Kassan… - Cardiovascular …, 2020 - Springer
The endothelium plays a pivotal role in maintaining vascular health. Obesity is a global
epidemic that has seen dramatic increases in both adult and pediatric populations. Obesity …

Identification of cancer stem cell characteristics in liver hepatocellular carcinoma by WGCNA analysis of transcriptome stemness index

KH Bai, SY He, LL Shu, WD Wang, SY Lin… - Cancer …, 2020 - Wiley Online Library
Cancer stem cells (CSCs) are characterized by self‐renewal and‐differential potential as
compared to common cancer cells and play an important role in the development and …

MicroRNA-27a (miR-27a) in solid tumors: a review based on mechanisms and clinical observations

J Zhang, Z Cao, G Yang, L You, T Zhang… - Frontiers in …, 2019 - frontiersin.org
MicroRNAs (miRNAs) are a family of highly conserved, non-coding single-stranded RNAs
transcribed as~ 70 nucleotide precursors to an 18–22 nucleotide product. miRNAs can …

CRISPR-based dissection of microRNA-23a~ 27a~ 24-2 cluster functionality in hepatocellular carcinoma

M Cui, Z Liu, S Wang, S Bae, H Guo, J Zhou, R Liu… - Oncogene, 2024 - nature.com
Abstract The miR-23a~ 27a~ 24-2 cluster, commonly upregulated in diverse cancers,
including hepatocellular carcinoma (HCC), raises questions about the specific functions of …

MicroRNAs: the link between the metabolic syndrome and oncogenesis

A Fodor, AL Lazar, C Buchman, B Tiperciuc… - International Journal of …, 2021 - mdpi.com
Metabolic syndrome (MetS) represents a cluster of disorders that increase the risk of a
plethora of conditions, in particular type two diabetes, cardiovascular diseases, and certain …

[HTML][HTML] Lycium barbarum polysaccharide (LBP) inhibits palmitic acid (PA)-induced MC3T3-E1 cell apoptosis by regulating miR-200b-3p/Chrdl1/PPARγ

L Jing, B Hu, QH Song - Food & Nutrition Research, 2020 - ncbi.nlm.nih.gov
Lycium barbarum polysaccharide (LBP) inhibits palmitic acid (PA)-induced MC3T3-E1 cell
apoptosis by regulating miR-200b-3p/Chrdl1/PPARγ - PMC Back to Top Skip to main content …

[PDF][PDF] Circulating exosomal microRNAs as potential biomarkers of hepatic injury and inflammation in a murine model of glycogen storage disease type 1a

R Resaz, D Cangelosi, M Morini… - Disease Models & …, 2020 - journals.biologists.com
Most patients affected by glycogen storage disease type 1a (GSD1a), an inherited metabolic
disorder caused by mutations in the enzyme glucose-6-phosphatase-α (G6Pase-α), develop …

[HTML][HTML] Rs3746444 T> C locus in miR-499 increases the susceptibility to hepatocellular carcinoma: A meta-analysis 14812 subjects

JK Jiang, HS Chen, WF Tang, Y Chen… - World Journal of …, 2023 - ncbi.nlm.nih.gov
BACKGROUND Recently, many investigations have suggested that the rs3746444 T> C
locus in the microRNA (miR)-499 gene may contribute to the occurrence of cancer …

microRNA-27a 在多种肝脏疾病发生发展中的作用机制.

罗昕, 徐铭益 - Journal of Clinical Hepatology/Linchuang …, 2020 - search.ebscohost.com
microRNA (miRNA) 是小分子非编码RNA, 可通过转录后基因表达的调控来调节多种生理和
病理功能. 越来越多的证据表明miRNA r 27a 在肝病的发展和发病机制中发挥了作用 …