TRPM8 channels: A review of distribution and clinical role
Ion channels are important therapeutic targets due to their plethoric involvement in
physiological and pathological consequences. The transient receptor potential cation …
physiological and pathological consequences. The transient receptor potential cation …
TRPM8 channels: Advances in structural studies and pharmacological modulation
C Izquierdo, M Martín-Martínez… - International Journal of …, 2021 - mdpi.com
The transient receptor potential melastatin subtype 8 (TRPM8) is a cold sensor in humans,
activated by low temperatures (> 10,< 28° C), but also a polymodal ion channel, stimulated …
activated by low temperatures (> 10,< 28° C), but also a polymodal ion channel, stimulated …
The role of transient receptor potential (TRP) channels in the transduction of dental pain
Dental pain is a common health problem that negatively impacts the activities of daily living.
Dentine hypersensitivity and pulpitis-associated pain are among the most common types of …
Dentine hypersensitivity and pulpitis-associated pain are among the most common types of …
Sustained Effects of Capsaicin Infusion into the Oropharynx on Swallowing in Perfused Rats
M Kaneko, Y Sugiyama, R Munekawa… - The …, 2024 - Wiley Online Library
Objectives To examine the sustained effects of oropharyngeal capsaicin stimulation on the
regulation of swallowing, we recorded the swallowing‐related nerve activities during …
regulation of swallowing, we recorded the swallowing‐related nerve activities during …
New and Evolving Treatments for Neurologic Dysphagia
Despite swallowing being a frequently performed daily function, it is highly complex. For a
safe swallow to occur, muscles within the head, neck, and thorax need to contract in a …
safe swallow to occur, muscles within the head, neck, and thorax need to contract in a …
[HTML][HTML] Transient receptor potential channels as an emerging therapeutic target for oropharyngeal dysphagia
MZ Hossain, J Kitagawa - Japanese Dental Science Review, 2023 - Elsevier
Oropharyngeal dysphagia is a serious health concern in older adults and patients with
neurological disorders. Current oropharyngeal dysphagia management largely relies on …
neurological disorders. Current oropharyngeal dysphagia management largely relies on …
A comparative study on the effect of acute pharyngeal stimulation with TRP agonists on the biomechanics and neurophysiology of swallow response in patients with …
Fluid thickening is the main compensatory strategy for patients with oropharyngeal
dysphagia (OD) associated with aging or neurological diseases, and there is still no …
dysphagia (OD) associated with aging or neurological diseases, and there is still no …
Targeting chemosensory ion channels in peripheral swallowing-related regions for the management of oropharyngeal dysphagia
MZ Hossain, H Ando, S Unno, J Kitagawa - International Journal of …, 2020 - mdpi.com
Oropharyngeal dysphagia, or difficulty in swallowing, is a major health problem that can lead
to serious complications, such as pulmonary aspiration, malnutrition, dehydration, and …
to serious complications, such as pulmonary aspiration, malnutrition, dehydration, and …
Oropharyngeal capsaicin exposure improves infant feeding performance in an animal model of superior laryngeal nerve damage
CE Edmonds, RZ German, LE Bond… - Journal of …, 2022 - journals.physiology.org
Sensorimotor feedback is critical to safe and effective swallowing. Because of this, sensory
interventions have the potential to treat dysphagia. One such treatment may be found in …
interventions have the potential to treat dysphagia. One such treatment may be found in …
Molecular and neural mechanism of dysphagia due to cancer
I Okuni, Y Otsubo, S Ebihara - International journal of molecular sciences, 2021 - mdpi.com
Cancer is one of the most common causes of death worldwide. Along with the advances in
diagnostic technology achieved through industry–academia partnerships, the survival rate of …
diagnostic technology achieved through industry–academia partnerships, the survival rate of …