Introduction Experimental and epidemiological studies suggest female sex hormones to
have long-lasting neuroprotective and anti-ageing properties. Surgically-induced …

In the CNS, there are widespread and diverse interactions between growth factors and
estrogen. Here we examine the interactions of estrogen and brain-derived neurotrophic …

Activity-dependent myelination is thought to contribute to adaptive neurological function.
However, the mechanisms by which activity regulates myelination and the extent to which …

Since its' discovery over 20 years ago, BDNF has been shown to play a key role in neuronal
survival, in promoting neuronal regeneration following injury, regulating transmitter systems …

During development, estrogen has a variety of effects on morphological and
electrophysiological properties of hippocampal neurons. Brain-derived neurotrophic factor …

Clinical research has demonstrated a significant sex difference in the occurrence of
depressive disorders. Beginning at pubertal onset, women report a higher incidence of …

Several lines of evidence support a role for brain-derived neurotrophic factor (BDNF)
alterations in the etiology of eating disorders (EDs). BDNF heterozygous knockout mice …

Finding an effective treatment for chronic neurodegenerative disorders still represents an
unmet goal. There is considerable evidence that such disorders represent a combination of …

Brain‐derived neurotrophic factor (BDNF) is an essential neurotrophin and regulation of its
expression is complex due to multiple 5′ untranslated exons which are separately spliced …

Objectives: Brain‐derived neurotrophic factor (BDNF) has been proposed as a candidate
molecule in the pathophysiology of major depressive disorder (MDD) and bipolar disorders …