Surgical menopause in association with cognitive function and risk of dementia: a systematic review and meta-analysis
MK Georgakis, T Beskou-Kontou, I Theodoridis… - …, 2019 - Elsevier
Introduction Experimental and epidemiological studies suggest female sex hormones to
have long-lasting neuroprotective and anti-ageing properties. Surgically-induced …
have long-lasting neuroprotective and anti-ageing properties. Surgically-induced …
Estrogen and brain-derived neurotrophic factor (BDNF) in hippocampus: complexity of steroid hormone-growth factor interactions in the adult CNS
HE Scharfman, NJ MacLusky - Frontiers in neuroendocrinology, 2006 - Elsevier
In the CNS, there are widespread and diverse interactions between growth factors and
estrogen. Here we examine the interactions of estrogen and brain-derived neurotrophic …
estrogen. Here we examine the interactions of estrogen and brain-derived neurotrophic …
Loss of adaptive myelination contributes to methotrexate chemotherapy-related cognitive impairment
AC Geraghty, EM Gibson, RA Ghanem, JJ Greene… - Neuron, 2019 - cell.com
Activity-dependent myelination is thought to contribute to adaptive neurological function.
However, the mechanisms by which activity regulates myelination and the extent to which …
However, the mechanisms by which activity regulates myelination and the extent to which …
Estrogen–BDNF interactions: implications for neurodegenerative diseases
F Sohrabji, DK Lewis - Frontiers in neuroendocrinology, 2006 - Elsevier
Since its' discovery over 20 years ago, BDNF has been shown to play a key role in neuronal
survival, in promoting neuronal regeneration following injury, regulating transmitter systems …
survival, in promoting neuronal regeneration following injury, regulating transmitter systems …
Estrogen regulates the development of brain-derived neurotrophic factor mRNA and protein in the rat hippocampus
DT Solum, RJ Handa - Journal of neuroscience, 2002 - Soc Neuroscience
During development, estrogen has a variety of effects on morphological and
electrophysiological properties of hippocampal neurons. Brain-derived neurotrophic factor …
electrophysiological properties of hippocampal neurons. Brain-derived neurotrophic factor …
Estrogenic mediation of serotonergic and neurotrophic systems: implications for female mood disorders
AP Borrow, NM Cameron - Progress in Neuro-Psychopharmacology and …, 2014 - Elsevier
Clinical research has demonstrated a significant sex difference in the occurrence of
depressive disorders. Beginning at pubertal onset, women report a higher incidence of …
depressive disorders. Beginning at pubertal onset, women report a higher incidence of …
Met66 in the brain-derived neurotrophic factor (BDNF) precursor is associated with anorexia nervosa restrictive type
Several lines of evidence support a role for brain-derived neurotrophic factor (BDNF)
alterations in the etiology of eating disorders (EDs). BDNF heterozygous knockout mice …
alterations in the etiology of eating disorders (EDs). BDNF heterozygous knockout mice …
The expanding role of BDNF: a therapeutic target for Alzheimer's disease?
F Fumagalli, G Racagni, MA Riva - The pharmacogenomics journal, 2006 - nature.com
Finding an effective treatment for chronic neurodegenerative disorders still represents an
unmet goal. There is considerable evidence that such disorders represent a combination of …
unmet goal. There is considerable evidence that such disorders represent a combination of …
Wheel running and environmental enrichment differentially modify exon‐specific BDNF expression in the hippocampus of wild‐type and pre‐motor symptomatic male …
Brain‐derived neurotrophic factor (BDNF) is an essential neurotrophin and regulation of its
expression is complex due to multiple 5′ untranslated exons which are separately spliced …
expression is complex due to multiple 5′ untranslated exons which are separately spliced …
Decreased levels of serum brain‐derived neurotrophic factor in both depressed and euthymic patients with unipolar depression and in euthymic patients with bipolar I …
P Monteleone, C Serritella, V Martiadis… - Bipolar disorders, 2008 - Wiley Online Library
Objectives: Brain‐derived neurotrophic factor (BDNF) has been proposed as a candidate
molecule in the pathophysiology of major depressive disorder (MDD) and bipolar disorders …
molecule in the pathophysiology of major depressive disorder (MDD) and bipolar disorders …