β2 integrins are heterodimeric surface receptors composed of a variable α (CD11a-CD11d)
and a constant β (CD18) subunit and are specifically expressed by leukocytes. The α …

Lessons from rare maladies: leukocyte adhesion deficiency sy... : Current Opinion in
Hematology Lessons from rare maladies: leukocyte adhesion deficiency syndromes …

Macrophage accumulation is a critical step during development of chronic inflammation,
initiating progression of many devastating diseases. Leukocyte-specific integrin α D β 2 …

Background Group 2 innate lymphoid cells (ILC2s) expand in the lungs of mice during type 2
inflammation induced by the fungal allergen Alternaria alternata. The increase in ILC2 …

CD11d/CD18 is the most recently discovered and least understood β2 integrin. Known
CD11d adhesive mechanisms contribute to both extravasation and mesenchymal migration …

The possibility of free radical reactions occurring in biological processes led to the
development and employment of novel methods and techniques focused on determining …

Integrins are a group of heterodimeric transmembrane receptors that play essential roles in
cell–cell and cell–matrix interaction. Integrins are important in many physiological processes …

Integrin αDβ2 is the most recently identified member of the leukocyte, or β2, subfamily of
integrin heterodimers. Its distribution and functions on human leukocytes have not been …

Background Malaria-associated acute respiratory distress syndrome (MA-ARDS) is a
potentially lethal complication of clinical malaria. Acute lung injury in MA-ARDS shares …

Neutrophil-macrophage interplay is a fine-tuning mechanism that regulates the innate
immune response during infection and inflammation. Cell surface receptors play an …