Exploring the frontiers of therapeutic breadth of antifungal peptides: A new avenue in antifungal drugs
I Ul Haq, S Maryam, DY Shyntum… - Journal of Industrial …, 2024 - academic.oup.com
The growing prevalence of fungal infections alongside rising resistance to antifungal drugs
poses a significant challenge to public health safety. At the close of the 2000s, major …
poses a significant challenge to public health safety. At the close of the 2000s, major …
Use of defensins to develop eco-friendly alternatives to synthetic fungicides to control phytopathogenic fungi and their mycotoxins
V Leannec-Rialland, V Atanasova, S Chereau… - Journal of Fungi, 2022 - mdpi.com
Crops are threatened by numerous fungal diseases that can adversely affect the availability
and quality of agricultural commodities. In addition, some of these fungal phytopathogens …
and quality of agricultural commodities. In addition, some of these fungal phytopathogens …
Defensin–lipid interactions in membrane targeting: mechanisms of action and opportunities for the development of antimicrobial and anticancer therapeutics
MJA Hein, M Kvansakul, FT Lay… - Biochemical Society …, 2022 - portlandpress.com
Defensins are a class of host defence peptides (HDPs) that often harbour antimicrobial and
anticancer activities, making them attractive candidates as novel therapeutics. In comparison …
anticancer activities, making them attractive candidates as novel therapeutics. In comparison …
Health implications and nutrient bioavailability of bioactive compounds in dry beans and other pulses
JA Wiesinger, F Marsolais… - Dry beans and pulses …, 2022 - Wiley Online Library
Pulse crops produced for direct human consumption (dry bean, dry pea, lentil, and chickpea)
are an important source of protein and complex carbohydrates for millions living throughout …
are an important source of protein and complex carbohydrates for millions living throughout …
Antifungal Activity, Structural Stability, and Immunomodulatory Effects on Human Immune Cells of Defensin from the Lentil Lens culinaris
EI Finkina, IV Bogdanov, AA Ignatova, MD Kanushkina… - Membranes, 2022 - mdpi.com
An increase in the frequency of mycoses and spreading of multidrug-resistant fungal
pathogens necessitates the search for new antifungal agents. Earlier, we isolated the novel …
pathogens necessitates the search for new antifungal agents. Earlier, we isolated the novel …
The C-terminus of panusin, a lobster β-defensin, is crucial for optimal antimicrobial activity and serum stability
β-defensins are one of the most abundant and studied families of antimicrobial peptides
(AMPs). Because of their selective toxicity to bacterial membranes and a broad spectrum of …
(AMPs). Because of their selective toxicity to bacterial membranes and a broad spectrum of …
Natural phytoalexins inspired the discovery of new biphenyls as potent antifungal agents for treatment of invasive fungal infections
With the aim of discovering novel and effective antifungal agents derived from natural
sources, a series of new biphenyls based on natural biphenyl phytoalexins were designed …
sources, a series of new biphenyls based on natural biphenyl phytoalexins were designed …
Fighting pathogenic yeasts with plant defensins and anti-fungal proteins from fungi
P Manzanares, M Giner-Llorca, JF Marcos… - Applied microbiology …, 2024 - Springer
Fungal infections represent a significant health risk worldwide. Opportunistic infections
caused by yeasts, particularly by Candida spp. and their virulent emerging isolates, have …
caused by yeasts, particularly by Candida spp. and their virulent emerging isolates, have …
Antifungal Plant Defensins as an Alternative Tool to Combat Candidiasis
EI Finkina, OV Shevchenko, SI Fateeva, AA Tagaev… - Plants, 2024 - mdpi.com
Currently, the spread of fungal infections is becoming an urgent problem. Fungi of the
Candida genus are opportunistic microorganisms that cause superficial and life-threatening …
Candida genus are opportunistic microorganisms that cause superficial and life-threatening …
Recent Discoveries of Antifungal Activity in Plant Antimicrobial Peptides
Abstract Background Antimicrobial peptides (AMPs) are positive-charged small molecules of
less than 50 amino acids, with antibacterial and antifungal properties. The main mechanism …
less than 50 amino acids, with antibacterial and antifungal properties. The main mechanism …