The majority of cancers are associated to cachexia, a severe form of weight loss mostly
accounted for by skeletal muscle wasting. Cancer patients are often treated with …

Cachexia is a wasting syndrome that may accompany a plethora of diseases, including
cancer, chronic obstructive pulmonary disease, aids, and rheumatoid arthritis. It is …

Recent studies have correlated physical activity with a better prognosis in cachectic patients,
although the underlying mechanisms are not yet understood. In order to identify the …

Voluntary wheel running in the mouse is used to assess physical performance and
endurance and to model exercise training as a way to enhance health. Wheel running is a …

Fatigue is a prominent symptom in many diseases and disorders and reduces quality of life
for many people. The lack of clear pathogenesis and failure of current interventions to …

Body weight loss, mostly due to the wasting of skeletal muscle and adipose tissue, is the
hallmark of the so-called cachexia syndrome. Cachexia is associated with several acute and …

Cancer-associated cachexia is a complex metabolic syndrome characterized by weight loss
and systemic inflammation. Muscle loss and fatty infiltration into muscle are associated with …

Emerging evidence suggests that the muscle microenvironment plays a prominent role in
cancer cachexia. We recently showed that NF‐kB‐induced Pax7 overexpression impairs the …

Simple Summary Cachexia is a deadly disease that accompanies many different types of
cancers. Animal studies on cachexia have so far mostly been conducted using young mice …

Exercise reduces the risk of developing a number of neurological disorders and increases
the efficiency of cellular energy production. However, overly strenuous exercise produces …