[HTML][HTML] Organs-on-chips technologies–A guide from disease models to opportunities for drug development
Current in-vitro 2D cultures and animal models present severe limitations in recapitulating
human physiopathology with striking discrepancies in estimating drug efficacy and side …
human physiopathology with striking discrepancies in estimating drug efficacy and side …
Biosensors based on mechanical and electrical detection techniques
T Chalklen, Q Jing, S Kar-Narayan - Sensors, 2020 - mdpi.com
Biosensors are powerful analytical tools for biology and biomedicine, with applications
ranging from drug discovery to medical diagnostics, food safety, and agricultural and …
ranging from drug discovery to medical diagnostics, food safety, and agricultural and …
Isolation of rare cells from cell mixtures by dielectrophoresis
PRC Gascoyne, J Noshari, TJ Anderson… - …, 2009 - Wiley Online Library
The application of dielectrophoretic field‐flow fractionation (depFFF) to the isolation of
circulating tumor cells (CTCs) from clinical blood specimens was studied using simulated …
circulating tumor cells (CTCs) from clinical blood specimens was studied using simulated …
Dielectric spectroscopy as a viable biosensing tool for cell and tissue characterization and analysis
The use of dielectric spectroscopy to carry out real time observations of cells and to extract a
wealth of information about their physiological properties has expanded in recent years. This …
wealth of information about their physiological properties has expanded in recent years. This …
Microfluidic chip with integrated electrical cell-impedance sensing for monitoring single cancer cell migration in three-dimensional matrixes
Cell migration has been recognized as one hallmark of malignant tumor progression. By
integrating the method of electrical cell–substrate impedance sensing (ECIS) with the …
integrating the method of electrical cell–substrate impedance sensing (ECIS) with the …
Circulating tumor cell enrichment based on physical properties
RA Harouaka, M Nisic… - Journal of laboratory …, 2013 - journals.sagepub.com
The metastatic dissemination and spread of malignant circulating tumor cells (CTCs)
accounts for more than 90% of cancer-related deaths. CTCs detach from a primary tumor …
accounts for more than 90% of cancer-related deaths. CTCs detach from a primary tumor …
Enrichment, detection and clinical significance of circulating tumor cells
Circulating Tumor Cells (CTCs) are shed from primary or secondary tumors into blood
circulation. Accessing and analyzing these cells provides a non-invasive alternative to tissue …
circulation. Accessing and analyzing these cells provides a non-invasive alternative to tissue …
An electrorotation technique for measuring the dielectric properties of cells with simultaneous use of negative quadrupolar dielectrophoresis and electrorotation
This paper presents an effective electrorotation technique for measuring the dielectric
properties of cells using a superposed electrical signal, which can simultaneously generate …
properties of cells using a superposed electrical signal, which can simultaneously generate …
Bioimpedance analysis for the characterization of breast cancer cells in suspension
The bioimpedance spectroscopy (BIS) technique is potentially a useful tool to differentiate
malignancy based on the variation of electrical properties presented by different tissues and …
malignancy based on the variation of electrical properties presented by different tissues and …
Dielectrophoretic manipulation of cancer cells and their electrical characterization
Electromanipulation and electrical characterization of cancerous cells is becoming a topic of
high interest as the results reported to date demonstrate a good differentiation among …
high interest as the results reported to date demonstrate a good differentiation among …