Evaluating parameters affecting drug fate at the intramuscular injection site

AJS McCartan, DW Curran, RJ Mrsny - Journal of Controlled Release, 2021 - Elsevier
Intramuscular (IM) injections are a well-established method of delivering a variety of
therapeutics formulated for parenteral administration. While the wide range of commercial IM …

Targeted intracluster supraclavicular brachial plexus block: too close for comfort

J Gadsden, S Orebaugh - British Journal of Anaesthesia, 2019 - bjanaesthesia.org
With the widespread adoption of ultrasound guidance for peripheral nerve blocks,
anaesthesiologists have generally agreed that it is prudent to place the needle in the same …

[HTML][HTML] Incidence of sub-perineural injection using a targeted intracluster supraclavicular ultrasound-guided approach in cadavers

S Retter, J Szerb, K Kwofie, P Colp, R Sandeski… - British journal of …, 2019 - Elsevier
Background Multi-injection targeted intracluster injection ultrasound-guided supraclavicular
brachial plexus block has been advocated to provide a faster onset of anaesthesia …

Extraplexus versus intraplexus ultrasound-guided interscalene brachial plexus block for ambulatory arthroscopic shoulder surgery: a randomized controlled trial

MW Harbell, K Kolodzie, M Behrends, CB Ma, S Kinjo… - PloS one, 2021 - journals.plos.org
Background This randomized study compared the efficacy and safety of extraplexus and
intraplexus injection of local anesthetic for interscalene brachial plexus block. Methods 208 …

A cadaver study investigating structures encountered by the needle during a retroclavicular approach to infraclavicular brachial plexus block

SF Sancheti, V Uppal, R Sandeski, MK Kwofie… - 2018 - rapm.bmj.com
Background and Objectives Retroclavicular block is designed to overcome the negative
aspects of the commonly utilized ultrasound-guided parasagittal approach to the …

Critical structures in the needle path of the costoclavicular brachial plexus block: a cadaver study

JG Bailey, S Donald, KM Kwesi… - Canadian Journal of …, 2021 - search.proquest.com
Purpose The costoclavicular block is a relatively novel alternative to the infraclavicular block.
We aimed to determine the anatomical structures vulnerable to needle injury during a …

Discriminative Ability of Dye Injected Into a Meat Model to Determine Accuracy of Ultrasound-Guided Injection

RG Brownbridge, MB Kiberd, D Werry, JG Bailey - 2023 - journals.lww.com
Methods Meat models containing a beef tendon (simulating a nerve) were injected with dye
in one of 3 locations: PN, intraneural, and intramuscular. Blinded assessors then …

A low dose of three local anesthetic solutions for interscalene blockade tested by thermal quantitative sensory testing: a randomized controlled trial

LA Sermeus, T Schepens, GH Hans… - Journal of Clinical …, 2019 - Springer
This randomized double-blind controlled trial compared the block characteristics of three low-
dose local anesthetics at different roots in an ultrasound-guided interscalene block, using …

India ink: a time-tested histological marker

J Szerb, K Kwofie, V Uppal - Regional Anesthesia & Pain Medicine, 2019 - rapm.bmj.com
In their letter to the editor, Boezaart and colleagues, highlight their recent work using diluted
heparinized whole blood as a marker of microscopic nerve anatomy, while casting …

Effects of stellate ganglion block on analgesia produced by cervical paravertebral block as established by quantitative sensory testing: a randomized controlled trial

LA Sermeus, LE Vanlinthout, GH Hans… - Pain …, 2018 - academic.oup.com
Objective To use quantitative sensory testing (QST) to assess whether a stellate ganglion
block (SGB) modulates the analgesia induced by cervical paravertebral block (CPVB) …