Acanthaster planci Inhibits PCSK9 and Lowers Cholesterol Levels in Rats

NN Kamaruddin, NA Hajri, Y Andriani, AF Abdul Manan… - Molecules, 2021 - mdpi.com
Atherosclerosis is the main cause of cardiovascular diseases which in turn, lead to the
highest number of mortalities globally. This pathophysiological condition is developed due …

Acanthaster planci Inhibits PCSK9 Gene Expression via Peroxisome Proliferator Response Element (PPRE) and Activation of MEK and PKC Signaling Pathways in …

NN Kamaruddin, LH Mohd Din, A Jack… - Pharmaceuticals, 2022 - mdpi.com
A constantly elevated level of low-density lipoprotein cholesterol (LDL-C) is mainly
associated with the development of atherosclerosis. The use of statins as a treatment for …

[PDF][PDF] PCSK9 inhibitory activity of marine-derived compounds, aaptaminoids, and benzamide originated from Aaptos aaptos and Acanthaster planci as a potential …

H Mohamad, MF Abd Razak… - Journal of Applied …, 2020 - japsonline.com
Atherosclerosis is an inflammatory disorder of the vasculature and one of the underlying
causes of cardiovascular diseases. Numerous preventative and therapeutic approaches are …

[引用][C] Methyl Benzoate from Acanthaster Planci Exhibits Lipid-lowering Activity in Hypercholesterolemic Sprague-Dawley Rat's Hepatocyte by Increasing Scavenger …

L Abu-Bakar, N Ismail… - International …, 2023 - Society of Pharmaceutical Sciences …