[HTML][HTML] Radiolabelling small and biomolecules for tracking and monitoring
MR Edelmann - RSC advances, 2022 - pubs.rsc.org
Radiolabelling small molecules with beta-emitters has been intensively explored in the last
decades and novel concepts for the introduction of radionuclides continue to be reported …
decades and novel concepts for the introduction of radionuclides continue to be reported …
Metabolism of peptide drugs and strategies to improve their metabolic stability
JF Yao, H Yang, YZ Zhao, M Xue - Current drug metabolism, 2018 - ingentaconnect.com
Background: Despite the therapeutic use of peptides is limited because of their metabolism
in vivo, there are no systematic reviews explaining degradation of peptides by peptidases …
in vivo, there are no systematic reviews explaining degradation of peptides by peptidases …
[HTML][HTML] Identification of impacted pathways and transcriptomic markers as potential mediators of pulmonary fibrosis in transgenic mice expressing human IGFBP5
XX Nguyen, L Renaud, C Feghali-Bostwick - International journal of …, 2021 - mdpi.com
Pulmonary fibrosis is a serious disease characterized by extracellular matrix (ECM)
component overproduction and remodeling. Insulin-like growth factor-binding protein 5 …
component overproduction and remodeling. Insulin-like growth factor-binding protein 5 …
[HTML][HTML] Identification of hub genes and immune cell infiltration characteristics in chronic rhinosinusitis with nasal polyps: Bioinformatics analysis and experimental …
Y Pan, L Wu, S He, J Wu, T Wang… - Frontiers in Molecular …, 2022 - frontiersin.org
The aim of our study is to reveal the hub genes related to the pathogenesis of chronic
rhinosinusitis with nasal polyps (CRSwNP) and their association with immune cell infiltration …
rhinosinusitis with nasal polyps (CRSwNP) and their association with immune cell infiltration …
Discovery of a Pentapeptide Antagonist to Human Neuromedin U Receptor 1
K Takayama, K Mori, Y Sasaki, A Taguchi… - ACS Medicinal …, 2024 - ACS Publications
Neuromedin U (NMU) activates two types of receptors (NMUR1 and NMUR2), and the
former is mainly expressed in the peripheral tissues, including the intestinal tract and lung …
former is mainly expressed in the peripheral tissues, including the intestinal tract and lung …
Improving the LC-MS/MS analysis of neuromedin U-8 and neuromedin S by minimizing their adsorption behavior and optimizing UHPLC and MS parameters
J Bongaerts, D De Bundel, I Smolders… - … of Pharmaceutical and …, 2023 - Elsevier
Neuromedin U (NmU) and neuromedin S (NmS) are two closely related neuropeptides
belonging to the neuromedin family. NmU usually occurs either as a truncated eight amino …
belonging to the neuromedin family. NmU usually occurs either as a truncated eight amino …
Tritium Labeling of Neuromedin S by Conjugation with [3H]N-Succinimidyl Propionate
MR Edelmann, J Erny, W Guba, M Hierl - ACS omega, 2023 - ACS Publications
The human neuropeptide neuromedin S (NMS) consists of 33 amino acids. The introduction
of tritium atoms into NMS has not been described so far. This represents a gap for using [3H] …
of tritium atoms into NMS has not been described so far. This represents a gap for using [3H] …
[HTML][HTML] Neuromedin U induces an invasive phenotype in CRC cells expressing the NMUR2 receptor
P Przygodzka, E Sochacka, K Soboska… - Journal of Experimental …, 2021 - Springer
Background Successful colorectal cancer (CRC) therapy often depends on the accurate
identification of primary tumours with invasive potential. There is still a lack of identified …
identification of primary tumours with invasive potential. There is still a lack of identified …
Unanticipated characteristics of a selective, potent Neuromedin-U receptor 2 agonist
S Mehrotra, S Lam, E Glenn, D Hymel… - ACS bio & med …, 2022 - ACS Publications
Neuromedin-U (NMU) mediates several physiological functions via its two cognate
receptors, NMUR1 and NMUR2. Disentangling the individual roles of each receptor has …
receptors, NMUR1 and NMUR2. Disentangling the individual roles of each receptor has …
Effects of neuromedin U-8 on stress responsiveness and hypothalamus-pituitary-adrenal axis activity in male C57BL/6J mice
A De Prins, W Allaoui, M Medrano… - Hormones and …, 2020 - Elsevier
Neuromedin U (NMU) is a highly conserved neuropeptide that has been implicated in the
stress response. To better understand how it influences various aspects of the stress …
stress response. To better understand how it influences various aspects of the stress …