Mesenchymal stromal cell homing: mechanisms and strategies for improvement

M Ullah, DD Liu, AS Thakor - Iscience, 2019 - cell.com
Mesenchymal stromal cells (MSCs) have been widely investigated for their therapeutic
potential in regenerative medicine, owing to their ability to home damaged tissue and serve …

[HTML][HTML] Homing and migration of mesenchymal stromal cells: how to improve the efficacy of cell therapy?

A De Becker, I Van Riet - World journal of stem cells, 2016 - ncbi.nlm.nih.gov
Mesenchymal stromal cells (MSCs) are currently being investigated for use in a wide variety
of clinical applications. For most of these applications, systemic delivery of the cells is …

Mesenchymal stem cell migration during bone formation and bone diseases therapy

P Su, Y Tian, C Yang, X Ma, X Wang, J Pei… - International journal of …, 2018 - mdpi.com
During bone modeling, remodeling, and bone fracture repair, mesenchymal stem cells
(MSCs) differentiate into chondrocyte or osteoblast to comply bone formation and …

[HTML][HTML] Oxygen in stem cell biology: a critical component of the stem cell niche

A Mohyeldin, T Garzón-Muvdi, A Quiñones-Hinojosa - Cell stem cell, 2010 - cell.com
The defining hallmark of stem cells is their ability to self-renew and maintain multipotency.
This capacity depends on the balance of complex signals in their microenvironment. Low …

Mesenchymal stromal cells and cutaneous wound healing: a comprehensive review of the background, role, and therapeutic potential

MS Hu, MR Borrelli, HP Lorenz… - Stem cells …, 2018 - Wiley Online Library
Cutaneous wound repair is a highly coordinated cascade of cellular responses to injury
which restores the epidermal integrity and its barrier functions. Even under optimal healing …

Mesenchymal stem cells migration homing and tracking

A Sohni, CM Verfaillie - Stem cells international, 2013 - Wiley Online Library
In this review, we discuss the migration and homing ability of mesenchymal stem cells
(MSCs) and MSC‐like cells and factors influencing this. We also discuss studies related to …

[HTML][HTML] Mesenchymal stem cell homing: the devil is in the details

JM Karp, GSL Teo - Cell stem cell, 2009 - cell.com
The study of MSC trafficking is clinically relevant for minimally invasive cell therapy to
promote regeneration of damaged tissue, to treat inflammation, and to promote …

Mesenchymal stem cells can be differentiated into endothelial cells in vitro

J Oswald, S Boxberger, B Jørgensen, S Feldmann… - Stem …, 2004 - academic.oup.com
Human bone marrow‐derived mesenchymal stem cells (MSCs) have the potential to
differentiate into mesenchymal tissues like osteocytes, chondrocytes, and adipocytes in vivo …

Enhancement of mesenchymal stem cell angiogenic capacity and stemness by a biomimetic hydrogel scaffold

KC Rustad, VW Wong, M Sorkin, JP Glotzbach… - Biomaterials, 2012 - Elsevier
In this study, we examined the capacity of a biomimetic pullulan–collagen hydrogel to create
a functional biomaterial-based stem cell niche for the delivery of mesenchymal stem cells …

Vasculotropic, paracrine actions of infused mesenchymal stem cells are important to the recovery from acute kidney injury

F Togel, K Weiss, Y Yang, Z Hu… - American Journal …, 2007 - journals.physiology.org
Acute kidney injury (AKI) is a major clinical problem in which a critical vascular,
pathophysiological component is recognized. We demonstrated previously that …