Synthetic systems powered by biological molecular motors

G Saper, H Hess - Chemical reviews, 2019 - ACS Publications
Biological molecular motors (or biomolecular motors for short) are nature's solution to the
efficient conversion of chemical energy to mechanical movement. In biological systems …

All wired up: an exploration of the electrical properties of microtubules and tubulin

AP Kalra, BB Eakins, SD Patel, G Ciniero, V Rezania… - ACS …, 2020 - ACS Publications
Microtubules are hollow, cylindrical polymers of the protein α, β tubulin, that interact
mechanochemically with a variety of macromolecules. Due to their mechanically robust …

Electronic energy migration in microtubules

AP Kalra, A Benny, SM Travis, EA Zizzi… - ACS Central …, 2023 - ACS Publications
The repeating arrangement of tubulin dimers confers great mechanical strength to
microtubules, which are used as scaffolds for intracellular macromolecular transport in cells …

[HTML][HTML] Electricity auto-generating skin patch promotes wound healing process by activation of mechanosensitive ion channels

TH Kim, WY Jeon, Y Ji, EJ Park, DS Yoon, NH Lee… - Biomaterials, 2021 - Elsevier
Electricity constitutes a natural biophysical component that preserves tissue homeostasis
and modulates many biological processes, including the repair of damaged tissues. Wound …

Modulation of microtubule properties and functions by encapsulation of nanomaterials using a Tau-derived peptide

H Inaba, K Matsuura - Bulletin of the Chemical Society of Japan, 2021 - academic.oup.com
Microtubules (MTs) are hollow cytoskeletons with typically 15 nm inner diameter, which are
crucial for various cellular activities including structural support, transport, and cell division …

Peptide nanomaterials designed from natural supramolecular systems

H Inaba, K Matsuura - The Chemical Record, 2019 - Wiley Online Library
Natural supramolecular assemblies exhibit unique structural and functional properties that
have been optimized over the course of evolution. Inspired by these natural systems, various …

Building on-chip cytoskeletal circuits via branched microtubule networks

M Zaferani, R Song, S Petry… - Proceedings of the …, 2024 - National Acad Sciences
Controllable platforms to engineer robust cytoskeletal scaffolds have the potential to create
novel on-chip nanotechnologies. Inspired by axons, we combined the branching …

[HTML][HTML] Electro-detachment of kinesin motor domain from microtubule in silico

J Průša, M Cifra - Computational and Structural Biotechnology Journal, 2023 - Elsevier
Kinesin is a motor protein essential in cellular functions, such as intracellular transport and
cell-division, as well as for enabling nanoscopic transport in bio-nanotechnology. Therefore …

Lab-on-chip microscope platform for electro-manipulation of a dense microtubules network

D Havelka, I Zhernov, M Teplan, Z Lánský… - Scientific Reports, 2022 - nature.com
Pulsed electric field (PEF) technology is promising for the manipulation of biomolecular
components and has potential applications in biomedicine and bionanotechnology …

All lit up: Exploring the photophysical properties of protein polymers

AP Kalra, S Biswas, I Mulrain, M Wang… - The Journal of …, 2023 - ACS Publications
Microtubules and actin filaments are protein polymers that play a variety of energy
conversion roles in the biological cell. While these polymers are being increasingly …