(Nano) platforms in bladder cancer therapy: Challenges and opportunities

M Ashrafizadeh, A Zarrabi… - Bioengineering & …, 2023 - Wiley Online Library
Urological cancers are among the most common malignancies around the world. In
particular, bladder cancer severely threatens human health due to its aggressive and …

Cell-based drug delivery systems and their in vivo fate

L Yang, Y Yang, Y Chen, Y Xu, J Peng - Advanced Drug Delivery Reviews, 2022 - Elsevier
Cell-based drug delivery systems (DDSs) have received attention recently because of their
unique biological properties and self-powered functions, such as excellent biocompatibility …

[HTML][HTML] Current research trends of nanomedicines

Q Liu, J Zou, Z Chen, W He, W Wu - Acta Pharmaceutica Sinica B, 2023 - Elsevier
Owing to the inherent shortcomings of traditional therapeutic drugs in terms of inadequate
therapeutic efficacy and toxicity in clinical treatment, nanomedicine designs have received …

Gene and photothermal combination therapy: principle, materials, and amplified anticancer intervention

F Tang, A Ding, Y Xu, Y Ye, L Li, R Xie, W Huang - Small, 2024 - Wiley Online Library
Gene therapy (GT) and photothermal therapy (PTT) have emerged as promising alternatives
to chemotherapy and radiotherapy for cancer treatment, offering noninvasiveness and …

Role of long non-coding RNAs (lncRNAs) in cancer: from subcellular localization to nanoparticles (NPs)-mediated targeted regulation

C Wei, Y Xu, Q Shen, R Li, X Xiao, PE Saw… - … Therapy-Nucleic Acids, 2023 - cell.com
Long non-coding RNAs (lncRNAs) are a class of RNA transcripts more than 200 nucleotides
in length that play crucial roles in cancer development and progression. With the rapid …

Advances in cell membrane-coated nanoparticles and their applications for bone therapy

Y Chen, M Zhu, B Huang, Y Jiang, J Su - Biomaterials Advances, 2023 - Elsevier
Due to the specific structure of natural bone, most of the therapeutics are incapable to be
delivered into the targeted site with effective concentrations. Nanotechnology has provided a …

[HTML][HTML] Cell membrane-camouflaged bufalin targets NOD2 and overcomes multidrug resistance in pancreatic cancer

W Zhang, Y Fan, J Zhang, D Shi, J Yuan… - Drug Resistance …, 2023 - Elsevier
Aims Multidrug resistance in pancreatic cancer poses a significant challenge in clinical
treatment. Bufalin (BA), a compound found in secretions from the glands of toads, may help …

Biomimetic nano-drug delivery system: an emerging platform for promoting tumor treatment

X Han, C Gong, Q Yang, K Zheng, Z Wang… - International Journal of …, 2024 - Taylor & Francis
With the development of nanotechnology, nanoparticles (NPs) have shown broad prospects
as drug delivery vehicles. However, they exhibit certain limitations, including low …

[HTML][HTML] Evaluation of cell membrane-derived nanoparticles as therapeutic carriers for pancreatic ductal adenocarcinoma using an in vitro tumour stroma model

C Tapeinos, G Torrieri, S Wang, JP Martins… - Journal of Controlled …, 2023 - Elsevier
Here, we fabricated nanoparticles made solely from the membrane of cells found in the
pancreatic tumour's microenvironment (TME), like the human MiaPaCa-2 cells and M2 …

Regulation of synovial macrophages polarization by mimicking efferocytosis for therapy of osteoarthritis

H Yang, Z Yu, S Ji, J Yan, Y Kong… - Advanced Functional …, 2022 - Wiley Online Library
The progression of osteoarthritis is associated with chronic synovitis caused by synovial
macrophage infiltration and proinflammatory M1 polarization. Accordingly, repolarization of …