Almond, hazelnut and walnut, three nuts for neuroprotection in Alzheimer's disease: A neuropharmacological review of their bioactive constituents
N Gorji, R Moeini, Z Memariani - Pharmacological Research, 2018 - Elsevier
An increase in the prevalence of Alzheimer's disease (AD) as a multifactorial
neurodegenerative disorder is an almost obvious issue in the world. Researches on natural …
neurodegenerative disorder is an almost obvious issue in the world. Researches on natural …
Fatty acid metabolism in the progression and resolution of CNS disorders
Recent advances in lipidomics and metabolomics have unveiled the complexity of fatty acid
metabolism and the fatty acid lipidome in health and disease. A growing body of evidence …
metabolism and the fatty acid lipidome in health and disease. A growing body of evidence …
[HTML][HTML] Aberrant lipid metabolism in the forebrain niche suppresses adult neural stem cell proliferation in an animal model of Alzheimer's disease
Lipid metabolism is fundamental for brain development and function, but its roles in normal
and pathological neural stem cell (NSC) regulation remain largely unexplored. Here, we …
and pathological neural stem cell (NSC) regulation remain largely unexplored. Here, we …
Stearoyl-CoA desaturase 5 (SCD5), a Δ-9 fatty acyl desaturase in search of a function
A large body of research has demonstrated that human stearoyl-CoA desaturase 1 (SCD1),
a universally expressed fatty acid Δ9-desaturase that converts saturated fatty acids (SFA) …
a universally expressed fatty acid Δ9-desaturase that converts saturated fatty acids (SFA) …
Neuroprotective effects of oleic acid in rodent models of cerebral ischaemia
J Song, YS Kim, DH Lee, SH Lee, HJ Park, D Lee… - Scientific reports, 2019 - nature.com
Oleic acid (OA) is released from brain phospholipids after cerebral ischaemia; however, its
role in ischaemic injury remains unknown. We hypothesised that OA has neuroprotective …
role in ischaemic injury remains unknown. We hypothesised that OA has neuroprotective …
Fatty acid synthesis in glial cells of the CNS
Fatty acids (FAs) are of crucial importance for brain homeostasis and neural function. Glia
cells support the high demand of FAs that the central nervous system (CNS) needs for its …
cells support the high demand of FAs that the central nervous system (CNS) needs for its …
FoxO3 deficiency in cortical astrocytes leads to impaired lipid metabolism and aggravated amyloid pathology
The rise of life expectancy of the human population is accompanied by the drastic increases
of age‐associated diseases, in particular Alzheimer's disease (AD), and underscores the …
of age‐associated diseases, in particular Alzheimer's disease (AD), and underscores the …
Targeting metabolic plasticity in glioma stem cells in vitro and in vivo through specific inhibition of c-Src by TAT-Cx43266-283
Background Glioblastoma is the most aggressive primary brain tumour and has a very poor
prognosis. Inhibition of c-Src activity in glioblastoma stem cells (GSCs, responsible for …
prognosis. Inhibition of c-Src activity in glioblastoma stem cells (GSCs, responsible for …
Pistacia genus as a potential source of neuroprotective natural products
Neuroprotective agents are able to defend the central nervous system against acute or
chronic neuronal injuries. Even with the progress made over the last decades, most of the …
chronic neuronal injuries. Even with the progress made over the last decades, most of the …
Gas chromatography–Mass Spectrometry-based cerebrospinal fluid metabolomics to reveal the Protection of Coptisine against transient focal cerebral ischemia …
J Zhang, A Qi, L Liu, C Cai, H Xu - Molecules, 2023 - mdpi.com
Coptisine (Cop) exerts a neuroprotective effect on central nervous system disease,
particularly ischemic stroke. However, its protective mechanism is still unclear. This study …
particularly ischemic stroke. However, its protective mechanism is still unclear. This study …