Selectivity enhancement in capillary electrophoresis by means of two-dimensional separation or dual detection concepts

A Beutner, T Herl, FM Matysik - Analytica Chimica Acta, 2019 - Elsevier
For the identification and quantification of analytes in complex samples, highly selective
analytical strategies are required. The selectivity of single separation techniques such as …

Localised quantitative structure–retention relationship modelling for rapid method development in reversed-phase high performance liquid chromatography

SH Park, M De Pra, PR Haddad, S Grosse… - … of Chromatography A, 2020 - Elsevier
Quantitative structure–retention relationships (QSRR) predicting the values of solute
“hydrophobicity” coefficient η′ in the approximate hydrophobic subtraction model (HSM) …

Unraveling peak asymmetry in chromatography through stochastic theory powered Monte Carlo simulations

LDC Bishop, A Misiura, NA Moringo… - Journal of Chromatography …, 2020 - Elsevier
An overarching theory of chromatography capable of modeling all analyte-stationary phase
interactions would enable predictive design of pharmaceutically relevant separations. The …

A mathematical model of a lateral electrochromatography device for continuous chiral separation

M Přibyl, P Izák, Z Slouka - Separation and Purification Technology, 2022 - Elsevier
The separation of enantiomers in a continuous manner represents a nontrivial task. Identical
physical properties of an enantiomeric pair render the standard separation methods …

Two-dimensional cellulose acetate membrane-supported mesoporous silica nanosheets for efficient nanosize-based molecules separation

Y Wei, Q Du, Y Wang, P Gao, Z Wang… - Journal of Molecular …, 2022 - Elsevier
Membrane separation technology plays an important role in nanosize-based molecules
separation. The two-dimensional mesoporous membranes have attracted considerable …

[HTML][HTML] Development of retention mechanism for the separation of carboxylic acids and inorganic anions in cryptand-based ion chromatography

D Lukács, K Horváth, P Hajós - Journal of Chromatography A, 2020 - Elsevier
The ion-exchange and complex forming equilibria were quantitatively described and
demonstrated in order to understand major factors in the control of selectivity in the …

Relating Chromatogram Lineshape to Microscale Surface Interactions Using Stochastic Theory and Chemometrics

LDC Bishop - 2021 - search.proquest.com
Pharmaceutical separations are necessary to mass-produce novel treatments for emerging
diseases. Rare, heterogeneous surface chemistry hampers separations by generating …

Data Analysis

O Jones, O Jones - Two-Dimensional Liquid Chromatography: Principles …, 2020 - Springer
Abstract 2DLC can resolve far more peaks than standard HPLC but it also produces far more
complex data. We are at a point in analytical science where running samples and …