The skeletal system is the basis of the vertebral body composition, which affords stabilization
sites for muscle attachment, protects vital organs, stores mineral ions, supplies places to the …

Osteoporosis, a metabolic bone disease characterized by low bone mineral density and
deterioration of bone microarchitecture, has led to a high risk of fatal osteoporotic fractures …

Autophagy is an evolutionarily conserved intracellular process and is considered one of the
main catabolism pathways. In the process of autophagy, cells are digested nonselectively or …

The onset of osteoporosis leads to a gradual decrease in bone density due to an imbalance
between bone formation and resorption. To achieve optimal drug efficacy with minimal side …

Insufficient bone formation and excessive bone resorption caused by estrogen deficiency
are the major factors resulting in the incidence of postmenopausal osteoporosis (PMOP) …

Osteoporosis is a highly prevalent disorder characterized by the loss of bone mass and
microarchitecture deterioration of bone tissue, attributed to various factors, including …

Epidermal growth factor receptor (EGFR) plays critical roles in cell proliferation,
tumorigenesis, and anti-cancer drug resistance. Overexpression and somatic mutations of …

Osteoporosis is a chronical, systemic skeletal disorder characterized by an increase in bone
resorption, which leads to reduced bone density. The reduction in bone mineral density and …

Autophagy is a ubiquitous cellular process, allowing the removal and recycling of damaged
proteins and organelles. At the basal level, this process plays a role in quality control, thus …

Osteoporosis is a common systemic skeletal metabolism disorder resulting in bone fragility
and increased fracture risk. Silent information regulator factor 2 homolog 1 (SIRT1) is crucial …