Comparison of AI with and without hand-crafted features to classify Alzheimer's disease in different languages

TM Kim, J Son, JW Chun, Y Lee, DJ Kim, IY Choi… - Computers in Biology …, 2024 - Elsevier
Abstract Background Detecting and analyzing Alzheimer's disease (AD) in its early stages is
a crucial and significant challenge. Speech data from AD patients can aid in diagnosing AD …

Exploring cross-tissue DNA methylation patterns: blood–brain CpGs as potential neurodegenerative disease biomarkers

V Mendonça, SC Soares-Lima… - Communications …, 2024 - nature.com
The difficulty of obtaining samples from certain human tissues has led to efforts to find
accessible sources to analyze molecular markers derived from DNA. In this study, we look …

[HTML][HTML] Charting the shared genetic architecture of Alzheimer's disease, cognition, and educational attainment, and associations with brain development

P Jaholkowski, S Bahrami, V Fominykh… - Neurobiology of …, 2024 - Elsevier
The observation that the risk of developing Alzheimer's disease is reduced in individuals
with high premorbid cognitive functioning, higher educational attainment, and occupational …

Understanding the (epi) genetic dysregulation in Parkinson's disease through an integrative brain competitive endogenous RNA network

RM Piergiorge, ATR de Vasconcelos… - Mechanisms of Ageing …, 2024 - Elsevier
Parkinson's disease (PD) is a rapidly growing neurodegenerative disorder characterized by
dopaminergic neuron loss in the substantia nigra pars compacta (SN) and aggregation of α …