A developmental and genetic classification for malformations of cortical development: update 2012
Malformations of cerebral cortical development include a wide range of developmental
disorders that are common causes of neurodevelopmental delay and epilepsy. In addition …
disorders that are common causes of neurodevelopmental delay and epilepsy. In addition …
The genetics of primary microcephaly
Primary microcephaly (MCPH, for “microcephaly primary hereditary”) is a disorder of brain
development that results in a head circumference more than 3 standard deviations below …
development that results in a head circumference more than 3 standard deviations below …
[图书][B] Volpe's Neurology of the Newborn
JJ Volpe, TE Inder, BT Darras, LS de Vries… - 2017 - books.google.com
A clear, engaging writing style, hundreds of full-color images, and new information
throughout make Volpe's Neurology of the Newborn, 6th Edition, an indispensable resource …
throughout make Volpe's Neurology of the Newborn, 6th Edition, an indispensable resource …
The role of the microtubule cytoskeleton in neurodevelopmental disorders
M Lasser, J Tiber, LA Lowery - Frontiers in cellular neuroscience, 2018 - frontiersin.org
Neurons depend on the highly dynamic microtubule (MT) cytoskeleton for many different
processes during early embryonic development including cell division and migration …
processes during early embryonic development including cell division and migration …
Recognition, signaling, and repair of DNA double-strand breaks produced by ionizing radiation in mammalian cells: the molecular choreography
LH Thompson - Mutation Research/Reviews in Mutation Research, 2012 - Elsevier
The faithful maintenance of chromosome continuity in human cells during DNA replication
and repair is critical for preventing the conversion of normal diploid cells to an oncogenic …
and repair is critical for preventing the conversion of normal diploid cells to an oncogenic …
Molecular genetics of human primary microcephaly: an overview
Autosomal recessive primary microcephaly (MCPH) is a neurodevelopmental disorder that
is characterised by microcephaly present at birth and non-progressive mental retardation …
is characterised by microcephaly present at birth and non-progressive mental retardation …
Condensins: universal organizers of chromosomes with diverse functions
T Hirano - Genes & development, 2012 - genesdev.cshlp.org
Condensins are multisubunit protein complexes that play a fundamental role in the structural
and functional organization of chromosomes in the three domains of life. Most eukaryotic …
and functional organization of chromosomes in the three domains of life. Most eukaryotic …
A centrosomal mechanism involving CDK5RAP2 and CENPJ controls brain size
J Bond, E Roberts, K Springell, S Lizarraga, S Scott… - Nature …, 2005 - nature.com
Autosomal recessive primary microcephaly is a potential model in which to research genes
involved in human brain growth. We show that two forms of the disorder result from …
involved in human brain growth. We show that two forms of the disorder result from …
Autosomal recessive primary microcephaly (MCPH): a review of clinical, molecular, and evolutionary findings
Autosomal recessive primary microcephaly (MCPH) is a neurodevelopmental disorder. It is
characterized by two principal features, microcephaly present at birth and nonprogressive …
characterized by two principal features, microcephaly present at birth and nonprogressive …
Neurodevelopmental protein Musashi-1 interacts with the Zika genome and promotes viral replication
A recent outbreak of Zika virus in Brazil has led to a simultaneous increase in reports of
neonatal microcephaly. Zika targets cerebral neural precursors, a cell population essential …
neonatal microcephaly. Zika targets cerebral neural precursors, a cell population essential …