Radiation therapy (RT) plays a key role in curative-intent treatments for head and neck
cancers. Its use is indicated as a sole therapy in early stage tumors or in combination with …

Perineural invasion (PNI), the neoplastic invasion of nerves, is a common pathologic finding
in head and neck cancer that is associated with poor clinical outcomes. PNI is a histologic …

Background Owing to its physical properties, intensity-modulated proton therapy (IMPT)
used for patients with oropharyngeal carcinoma has the ability to reduce the dose to organs …

Radiation therapy plays an integral role in the management of head and neck cancers
(HNCs). While most HNC patients have historically been treated with photon-based …

Use of proton beam therapy has expanded, with the number of proton centres rapidly
increasing not only in the USA but also worldwide. The physical characteristics of the proton …

While proton radiation therapy offers substantially better dose distribution characteristics
than photon radiation therapy in certain clinical applications, data demonstrating a …

Importance Patients with nonmetastatic nasopharyngeal carcinoma (NPC) are primarily
treated by radiotherapy with curative intent with or without chemotherapy and often …

Precision radiotherapy, which accurately delivers the dose on a tumor and confers little or no
irradiation to the surrounding normal tissue and organs, results in maximum tumor control …

Purpose A single-institution prospective study was conducted to assess disease control and
toxicity of proton therapy for patients with head and neck cancer. Methods and Materials …

Because of its sharp lateral penumbra and steep distal fall-off, proton therapy offers
dosimetric advantages over photon therapy. In head and neck cancer, proton therapy has …