Extracorporeal membrane oxygenation (ECMO) is a technology capable of providing short-
term mechanical support to the heart, lungs or both. Over the last decade, the number of …

Nearly a century after the significance of the human complement system was recognized, we
have come to realize that its functions extend far beyond the elimination of microbes …

The development of extracorporeal life support technology has added a new dimension to
the care of critically ill patients who fail conventional treatment options. Extracorporeal …

Objectives: Cardiac surgery, including coronary artery bypass, cardiac valve, and aortic
procedures, is among the most common surgical procedures performed in the United States …

Extracorporeal life support (ECLS) encompasses a wide range of extracorporeal modalities
that offer short-and intermediate-term mechanical support to the failing heart or lung. Apart …

The glycocalyx is a layer coating the luminal surface of vascular endothelial cells. It is vital
for endothelial function as it participates in microvascular reactivity, endothelium interaction …

Background Cardiopulmonary bypass (CPB) is often associated with degrees of complex
inflammatory response mediated by various cytokines. This response can, in severe cases …

Cardiopulmonary bypass (CPB) is a unique clinical scenario that results in widespread
activation of the hemostatic system. However, surgery also results in normal increases in …

Background Cardiopulmonary bypass (CPB) surgery initiates a systemic inflammatory
response, which is associated with postoperative morbidity and mortality. Hemoadsorption …

Objective Ventilator-associated pneumonia (VAP) is the most common and serious
nosocomial infection that threatens patients who have undergone cardiac surgery. This …