Our understanding of the hepatic consequences of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infection and its resultant coronavirus disease 2019 (COVID …

Liver transplantation offers live-saving therapy for patients with complications of cirrhosis
and stage T2 hepatocellular carcinoma. The demand for organs far outstrips the supply, and …

The first human orthotopic liver transplantation (LT) in Europe was performed by Sir Roy
Calne in Cambridge in 1968 [1], only one year after the first successful human liver …

The average age of liver transplant donors and recipients has increased over the years.
Independent of the cause of liver disease, older candidates have more comorbidities, higher …

Potent immunosuppressive drugs have significantly improved early patient survival after
liver transplantation (LT). However, long‐term results remain unsatisfactory because of …

Short-term patient and graft outcomes continue to improve after kidney and liver
transplantation, with 1-year survival rates over 80%; however, improving longer-term …

Great progress has been made in the field of liver transplantation over the past two decades.
This progress, however, also brings up the next set of challenges: First, organ shortage …

Chimeric antigen receptors (CARs) have shown remarkable ability to re-direct T cells to
target CD19-expressing tumours, resulting in remission rates of up to 90% in individuals with …

Promoting immune tolerance to transplanted organs can minimize the amount of
immunosuppressive drugs that patients need to take, reducing lifetime risks of mortality and …

The Banff Working Group on Liver Allograft Pathology reviewed and discussed literature
evidence regarding antibody-mediated liver allograft rejection at the 11th (Paris, France …