Internalization mechanisms of cell-penetrating peptides
I Ruseska, A Zimmer - Beilstein journal of nanotechnology, 2020 - beilstein-journals.org
In today's modern era of medicine, macromolecular compounds such as proteins, peptides
and nucleic acids are dethroning small molecules as leading therapeutics. Given their …
and nucleic acids are dethroning small molecules as leading therapeutics. Given their …
Endocytosis of abiotic nanomaterials and nanobiovectors: Inhibition of membrane trafficking
P Makvandi, M Chen, R Sartorius, A Zarrabi… - Nano Today, 2021 - Elsevier
Humans are exposed to nanoscopical nanobiovectors (eg coronavirus SARS-CoV-2) as
well as abiotic metal/carbon-based nanomaterials that enter cells serendipitously or …
well as abiotic metal/carbon-based nanomaterials that enter cells serendipitously or …
Liquid-like protein interactions catalyse assembly of endocytic vesicles
KJ Day, G Kago, L Wang, JB Richter, CC Hayden… - Nature Cell …, 2021 - nature.com
During clathrin-mediated endocytosis, dozens of proteins assemble into an interconnected
network at the plasma membrane. As initiators of endocytosis, Eps15 and Fcho1/2 …
network at the plasma membrane. As initiators of endocytosis, Eps15 and Fcho1/2 …
[HTML][HTML] A selective autophagy pathway for phase-separated endocytic protein deposits
Autophagy eliminates cytoplasmic content selected by autophagy receptors, which link
cargo to the membrane-bound autophagosomal ubiquitin-like protein Atg8/LC3. Here, we …
cargo to the membrane-bound autophagosomal ubiquitin-like protein Atg8/LC3. Here, we …
Cytoplasmic short linear motifs in ACE2 and integrin β3 link SARS-CoV-2 host cell receptors to mediators of endocytosis and autophagy
J Kliche, H Kuss, M Ali, Y Ivarsson - Science signaling, 2021 - science.org
The spike protein of SARS-CoV-2 binds the angiotensin-converting enzyme 2 (ACE2) on the
host cell surface and subsequently enters host cells through receptor-mediated endocytosis …
host cell surface and subsequently enters host cells through receptor-mediated endocytosis …
From flat to curved clathrin: controlling a plastic ratchet
KA Sochacki, JW Taraska - Trends in cell biology, 2019 - cell.com
Clathrin-mediated endocytosis (CME) is the primary mechanism eukaryotic cells use to
internalize material. New imaging tools are revealing the nanoscale structural dynamics of …
internalize material. New imaging tools are revealing the nanoscale structural dynamics of …
Clathrin: the molecular shape shifter
KM Wood, CJ Smith - Biochemical Journal, 2021 - portlandpress.com
Clathrin is best known for its contribution to clathrin-mediated endocytosis yet it also
participates to a diverse range of cellular functions. Key to this is clathrin's ability to …
participates to a diverse range of cellular functions. Key to this is clathrin's ability to …
Mechanistic-based classification of endocytosis-related inhibitors: Does it aid in assigning drugs against SARS-CoV-2?
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) canonically utilizes
clathrin-mediated endocytosis (CME) and several other endocytic mechanisms to invade …
clathrin-mediated endocytosis (CME) and several other endocytic mechanisms to invade …
O-GlcNAc Dynamics: The Sweet Side of Protein Trafficking Regulation in Mammalian Cells
A Ben Ahmed, Q Lemaire, J Scache, C Mariller… - Cells, 2023 - mdpi.com
The transport of proteins between the different cellular compartments and the cell surface is
governed by the secretory pathway. Alternatively, unconventional secretion pathways have …
governed by the secretory pathway. Alternatively, unconventional secretion pathways have …
Control of clathrin-mediated endocytosis by NIMA family kinases
Endocytosis, the process by which cells internalize plasma membrane and associated
cargo, is regulated extensively by posttranslational modifications. Previous studies …
cargo, is regulated extensively by posttranslational modifications. Previous studies …