Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease that mainly affects
synovial joints. During the course of RA, the synovium transforms into hyperplastic invasive …

The C‐type lectin domain (CTLD) group 14 family of transmembrane glycoproteins consist of
thrombomodulin, CD 93, CLEC 14A and CD 248 (endosialin or tumour endothelial marker …

Atherogenesis involves an interplay of inflammation, tissue remodeling and cellular
transdifferentiation (CTD), making it especially difficult to precisely delineate its …

Abstract Purpose of Review Idiopathic pulmonary fibrosis (IPF) is the most common form of
interstitial lung disease of unknown etiopathogenesis with mean survival of 3–5 years and …

Cells present in the adventitia, or outermost layer of the blood vessel, contribute to the
progression of vascular diseases, such as atherosclerosis, hypertension, and aortic …

The C-type lectin domain containing group 14 family members CLEC14A and CD93 are
proteins expressed by endothelium and are implicated in tumour angiogenesis. CD248 …

The use of mouse genetic tools to track and manipulate fibroblasts has provided invaluable
in vivo information regarding the activities of these cells. Recently, many new mouse strains …

Introduction CD248 (endosialin) is a stromal cell marker expressed on fibroblasts and
pericytes. During liver injury, myofibroblasts are the main source of fibrotic matrix. Objective …

Abstract CD248/endosialin/TEM1 is a type 1 transmembrane glycoprotein found on the
plasma membrane of activated mesenchymal cells. CD248 functions during embryo …

Background In spite of new treatments, the incidence of type 2 diabetes (T2D) and its
morbidities continue to rise. The key feature of T2D is resistance of adipose tissue and other …