Specialized pro-resolving mediators (SPMs) are enzymatically derived from essential fatty
acids and have important roles in orchestrating the resolution of tissue inflammation—that is …

The acute inflammatory response is host-protective to contain foreign invaders. Many of
today's pharmacopeia that block pro-inflammatory chemical mediators can cause serious …

The resolution of the inflammatory response is highly regulated by the timely biosynthesis of
a number of endogenous lipid mediators. Among these, lipoxins (LX) and their 15-epimers …

Airborne pathogens and environmental stimuli evoke immune responses in the lung. It is
critical to health that these responses be controlled to prevent tissue damage and the …

Inflammation is an essential host defence against infection, but can be damaging when
excessive. Resolution of inflammation is an active process, and the pro‐resolution effects of …

Background Chagas disease, caused by the protozoan Trypanosoma cruzi, is endemic in
Latin America and is widely distributed worldwide because of migration. In 30% of cases …

Inflammation is a critical component in the pathophysiology of numerous disease processes,
with most therapeutic modalities focusing on its inhibition in order to achieve treatment …

The Mediterranean diet (MedDiet) consists of consumption of vegetables and healthy oils
and have beneficial effects on metabolic and inflammatory diseases. Our goal here is to …

Recent clinical trials investigating treatment of chronic indeterminate Chagas disease with
two re-purposed azole anti-fungal drugs, posaconazole and ravuconazole, revealed their …

The most severe clinical manifestations of the horrifying COVID-19 disease, that claimed
millions of lives during the pandemic time, were Acute respiratory distress syndrome …