I. Executive Summary Background The 5 years since the publication of the first International
Consensus Statement on Allergy and Rhinology: Rhinosinusitis (ICAR‐RS) has witnessed …

Chronic rhinosinusitis (CRS) affects up to 12% of the general population and is traditionally
divided into two main phenotypic subsets, based on the presence of nasal polyps …

Importance Burning mouth syndrome is a chronic oral pain disorder that is characterized by
a generalized or localized burning sensation without the presence of any specific mucosal …

Background & aims Nasal obstruction caused by nasal septal deviation is very bothersome
and, therefore, can affect the patient's emotional state. However, little is known about the …

Asthma is a chronic heterogeneous airway disease. Common comorbid conditions are often
disproportionately present in severe asthma. Optimal care of patients with asthma requires …

Rhinosinusitis is one of the most common inflammatory diseases. It has been recognized
that intracranial vessels are involved and there might be an association with stroke …

The association between glaucoma and the risk of obstructive sleep apnea (OSA) has not
been fully evaluated. Therefore, this study aimed to investigate the prospective association …

Background Chronic rhinosinusitis (CRS) is often associated with other comorbidities due to
chronic inflammation. However, no population-based, longitudinal study has investigated …

Objectives/Hypothesis Psychological comorbidity is common in patients with chronic
rhinosinusitis (CRS) and is correlated with decreased overall and disease‐specific quality of …

Ototoxic medications can lead to significant morbidity. Thus, pre-marketing clinical trials
have assessed new drugs that have ototoxic potential. Nevertheless, several ototoxic side …