Therapeutic potential of intermittent hypoxia: a matter of dose
A Navarrete-Opazo, GS Mitchell - American Journal of …, 2014 - journals.physiology.org
Intermittent hypoxia (IH) has been the subject of considerable research in recent years, and
triggers a bewildering array of both detrimental and beneficial effects in multiple …
triggers a bewildering array of both detrimental and beneficial effects in multiple …
Therapeutic acute intermittent hypoxia: A translational roadmap for spinal cord injury and neuromuscular disease
We review progress towards greater mechanistic understanding and clinical translation of a
strategy to improve respiratory and non-respiratory motor function in people with …
strategy to improve respiratory and non-respiratory motor function in people with …
Daily intermittent hypoxia enhances walking after chronic spinal cord injury: a randomized trial
Objectives: To test the hypothesis that daily acute intermittent hypoxia (dAIH) and dAIH
combined with overground walking improve walking speed and endurance in persons with …
combined with overground walking improve walking speed and endurance in persons with …
[HTML][HTML] Time domains of the hypoxic ventilatory response and their molecular basis
ME Pamenter, FL Powell - Comprehensive Physiology, 2016 - ncbi.nlm.nih.gov
Ventilatory responses to hypoxia vary widely depending on the pattern and length of hypoxic
exposure. Acute, prolonged, or intermittent hypoxic episodes can increase or decrease …
exposure. Acute, prolonged, or intermittent hypoxic episodes can increase or decrease …
Unexpected benefits of intermittent hypoxia: enhanced respiratory and nonrespiratory motor function
Intermittent hypoxia (IH) is most often thought of for its role in morbidity associated with sleep-
disordered breathing, including central nervous system pathology. However, recent …
disordered breathing, including central nervous system pathology. However, recent …
[HTML][HTML] Activating injury-responsive genes with hypoxia enhances axon regeneration through neuronal HIF-1α
Injured peripheral neurons successfully activate a proregenerative transcriptional program
to enable axon regeneration and functional recovery. How transcriptional regulators …
to enable axon regeneration and functional recovery. How transcriptional regulators …
Intermittent hypoxia and neurorehabilitation
In recent years, it has become clear that brief, repeated presentations of hypoxia [ie, acute
intermittent hypoxia (AIH)] can boost the efficacy of more traditional therapeutic strategies in …
intermittent hypoxia (AIH)] can boost the efficacy of more traditional therapeutic strategies in …
Hypoxia‐induced phrenic long‐term facilitation: emergent properties
As in other neural systems, plasticity is a hallmark of the neural system controlling breathing.
One spinal mechanism of respiratory plasticity is phrenic long‐term facilitation (pLTF) …
One spinal mechanism of respiratory plasticity is phrenic long‐term facilitation (pLTF) …
[HTML][HTML] Rapid and robust restoration of breathing long after spinal cord injury
PM Warren, SC Steiger, TE Dick… - Nature …, 2018 - nature.com
There exists an abundance of barriers that hinder functional recovery following spinal cord
injury, especially at chronic stages. Here, we examine the rescue of breathing up to 1.5 …
injury, especially at chronic stages. Here, we examine the rescue of breathing up to 1.5 …
Transplantation of neural progenitors and V2a interneurons after spinal cord injury
There is growing interest in the use of neural precursor cells to treat spinal cord injury (SCI).
Despite extensive pre-clinical research, it remains unclear as to which donor neuron …
Despite extensive pre-clinical research, it remains unclear as to which donor neuron …