[HTML][HTML] Trends in pharmaceutical analysis and quality control by modern Raman spectroscopic techniques

A Silge, K Weber, D Cialla-May… - TrAC Trends in …, 2022 - Elsevier
The application of Raman spectroscopic methods in life science applications has entered a
new era due to advances in instrumentation, miniaturization and, most importantly …

In vitro models of axon regeneration

H Al-Ali, SR Beckerman, JL Bixby, VP Lemmon - Experimental neurology, 2017 - Elsevier
A variety of in vitro models have been developed to understand the mechanisms underlying
the regenerative failure of central nervous system (CNS) axons, and to guide pre-clinical …

High-throughput screening Raman spectroscopy platform for label-free cellomics

IW Schie, J Rüger, AS Mondol, A Ramoji… - Analytical …, 2018 - ACS Publications
We present a high-throughput screening Raman spectroscopy (HTS-RS) platform for a rapid
and label-free macromolecular fingerprinting of tens of thousands eukaryotic cells. The …

PINK1 phosphorylates ubiquitin predominantly in astrocytes

SK Barodia, LJ McMeekin, RB Creed… - NPJ Parkinson's …, 2019 - nature.com
Loss-of-function mutations in PINK1 are causally linked to recessively inherited Parkinson's
disease (PD), with marked loss of dopaminergic neurons in the substantia nigra that are …

Gas6 promotes oligodendrogenesis and myelination in the adult central nervous system and after lysolecithin-induced demyelination

S Goudarzi, A Rivera, AM Butt, S Hafizi - ASN neuro, 2016 - journals.sagepub.com
A key aim of therapy for multiple sclerosis (MS) is to promote the regeneration of
oligodendrocytes and remyelination in the central nervous system (CNS). The present study …

Pharmacological activation of mediodorsal thalamic GABA-A receptors modulates morphine/cetirizine-induced changes in the prefrontal cortical GFAP expression in a …

N Asgharpour-Masouleh, A Rezayof… - Behavioural Brain …, 2023 - Elsevier
The present study investigated the involvement of mediodorsal thalamic (MD) GABA-A
receptors in cetirizine/morphine-induced anti-allodynia using a rat model of neuropathic …

Compounds co-targeting kinases in axon regulatory pathways promote regeneration and behavioral recovery after spinal cord injury in mice

KM Mah, W Wu, H Al-Ali, Y Sun, Q Han, Y Ding… - Experimental …, 2022 - Elsevier
Recovery from spinal cord injury (SCI) and other central nervous system (CNS) trauma is
hampered by limits on axonal regeneration in the CNS. Regeneration is restricted by the …

High content analysis in amyotrophic lateral sclerosis

F Rinaldi, D Motti, L Ferraiuolo, BK Kaspar - Molecular and cellular …, 2017 - Elsevier
Amyotrophic lateral sclerosis (ALS) is a devastating disease characterized by the
progressive loss of motor neurons. Neurons, astrocytes, oligodendrocytes and microglial …

Reactive Astrocyte Gliosis: Production of Inhibitory Molecules

MT Joghataei, F Azedi, S Mehrabi - Spinal Cord Injury Therapy, 2019 - books.google.com
The astrocytic cell responses to injury have been extensively studied in a variety of
experimental models, and the term “astrogliosis” is often used to describe the astrocyte …

[PDF][PDF] Immunomodulatory effect of a purified peptide fraction isolated from Mesobuthus eupeus scorpion venom on astrocytoma cell line (1321N1)

B Masihipour, RH HOSSEINI… - Asia Pacific Journal of …, 2020 - academia.edu
Abstract Objective (s): Multiple Sclerosis is a central nervous system disease which belongs
to the category of autoimmune diseases. The prevalence of this disease in Iran is …