Clinical and regulatory concerns of biosimilars: a review of literature

V Halimi, A Daci, K Ancevska Netkovska… - International journal of …, 2020 - mdpi.com
Although biosimilars have been part of clinical practice for more than a decade, healthcare
professionals (HCPs) do not fully accept them. This is because of the perception that …

Anti-VEGF and other novel therapies for neovascular age-related macular degeneration: an update

M Parravano, E Costanzo, G Scondotto, G Trifirò… - BioDrugs, 2021 - Springer
Age-related macular degeneration (AMD) is a leading cause of visual impairment and
blindness in older adults. The prognosis for the neovascular type of advanced AMD …

Rationale, opportunities, and reality of biosimilar medications

GH Lyman, R Zon, RD Harvey… - New England Journal of …, 2018 - Mass Medical Soc
Can Biosimilar Drugs Bring Down Health Care Costs? Biosimilars work like established
therapeutic agents but have some dissimilarities based on differences in production. These …

Current and future roles of biosimilars in oncology practice

S Konstantinidou, A Papaspiliou… - Oncology …, 2020 - spandidos-publications.com
Biologics have been used increasingly in the treatment and supportive care of cancer;
however, their high cost places a significant burden on healthcare systems. The expiration of …

Indian biosimilars and vaccines at crossroads–replicating the success of pharmagenerics

S Panda, PK Singh, S Mishra, S Mitra, P Pattnaik… - Vaccines, 2023 - mdpi.com
Background: The global pharma sector is fast shifting from generics to biologics and
biosimilars with the first approval in Europe in 2006 followed by US approval in 2015. In the …

Transforming drug design: Innovations in computer-aided discovery for biosimilar agents

S Askari, A Ghofrani, H Taherdoost - BioMedInformatics, 2023 - mdpi.com
In pharmaceutical research and development, pursuing novel therapeutics and optimizing
existing drugs have been revolutionized by the fusion of cutting-edge technologies and …

A bibliometric analysis of the global research on biosimilars

A Hernández-Vásquez, CA Alarcon-Ruiz… - … policy and practice, 2018 - Taylor & Francis
Background Biosimilars could be a promising option to help decrease healthcare costs and
expand access to treatment. There is no previous evidence of a global bibliometric analysis …

Infliximab biosimilar for treating neurosarcoidosis: tolerance and efficacy in a retrospective study including switch from the originator and initiation of treatment

Q Riller, C Cotteret, H Junot, N Benameur… - Journal of …, 2019 - Springer
Objectives Infliximab is increasingly used to treat neurosarcoidosis. We aimed to determine
the efficacy and tolerance of an infliximab biosimilar for treating neurosarcoidosis. Methods …

A phase II, multicenter, open-label trial to evaluate the safety and efficacy of ISU303 (Agalsidase beta) in patients with Fabry disease

S Hwang, BH Lee, WS Kim, DS Kim, CK Cheon… - Medicine, 2022 - journals.lww.com
Background: Fabry disease (FD) is caused by a deficiency in the activity of the lysosomal
enzyme, α-galactosidase A (α-Gal A), which leads to globotriaosylceramide (Gb3) …

Assessment of the differences between generic and biosimilar drugs: a brief literature review

R Sayah, S Awada, L Ismaiil… - Journal of Generic …, 2023 - journals.sagepub.com
Generic Drugs are copies of small chemical drugs identical to their reference drug by dose,
form, safety, strength, mode of administration, quality, performance, and intended purpose …