Myeloid-derived suppressor cells (MDSCs) are pathologically activated neutrophils and
monocytes with potent immunosuppressive activity. They are implicated in the regulation of …

Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of cells
generated during a large array of pathologic conditions ranging from cancer to obesity …

Infections in the first year of life are common and often severe. The newborn host
demonstrates both quantitative and qualitative differences to the adult in nearly all aspects of …

The early stages of life are associated with increased susceptibility to infection, which is in
part due to an ineffective immune system. In the context of infection, the immune system …

Recent findings have uncovered novel fascinating aspects of the biology of neutrophils,
which ultimately attribute to these cells a broader role in inflammation and immunity. One …

Purpose: Myeloid-derived suppressor cells (MDSC) are a heterogeneous group of
pathologically expanded myeloid cells with immunosuppressive activity. In human disease …

Myeloid-derived suppressor cells (MDSCs) are pathologically activated and relatively
immature myeloid cells that have been implicated in the immunological regulation of many …

The developing human fetus generates both tolerogenic and protective immune responses
in response to the unique requirements of gestation. Thus, a successful human pregnancy …

Myeloid-derived suppressor cells (MDSCs) were initially identified in humans and mice with
cancer where they profoundly suppress T cell–and NK cell–mediated antitumor immunity …

The early life immune system is characterized by unique developmental milestones.
Functionally diverse immune cells arise from distinct waves of hematopoietic stem cells, a …