The structural and functional complexity of the integrative hypothalamus

H Fong, J Zheng, D Kurrasch - Science, 2023 - science.org
The hypothalamus (“hypo” meaning below, and “thalamus” meaning bed) consists of
regulatory circuits that support basic life functions that ensure survival. Sitting at the interface …

Antitumor effects of fecal microbiota transplantation: Implications for microbiome modulation in cancer treatment

H Xu, C Cao, Y Ren, S Weng, L Liu, C Guo… - Frontiers in …, 2022 - frontiersin.org
Fecal microbiome transplantation (FMT) from healthy donors is one of the techniques for
restoration of the dysbiotic gut, which is increasingly being used to treat various diseases …

Host extracellular vesicles confer cytosolic access to systemic LPS licensing non-canonical inflammasome sensing and pyroptosis

P Kumari, SO Vasudevan, AJ Russo, SS Wright… - Nature cell …, 2023 - nature.com
Intracellular surveillance for systemic microbial components during homeostasis and
infections governs host physiology and immunity. However, a long-standing question is how …

[HTML][HTML] Gut microbiota suppress feeding induced by palatable foods

J Ousey, JC Boktor, SK Mazmanian - Current Biology, 2023 - cell.com
Feeding behaviors depend on intrinsic and extrinsic factors including genetics, food
palatability, and the environment. 1, 2, 3, 4, 5 The gut microbiota is a major environmental …

Influence of the gut microbiota on satiety signaling

JJAJ Bastings, K Venema, EE Blaak… - Trends in Endocrinology & …, 2023 - cell.com
Recent studies show a link between the gut microbiota and the regulation of satiety and
energy intake, processes that contribute to the development and pathophysiology of …

Psychological stress-induced microbial metabolite indole-3-acetate disrupts intestinal cell lineage commitment

W Wei, Y Liu, Y Hou, S Cao, Z Chen, Y Zhang, X Cai… - Cell Metabolism, 2024 - cell.com
The brain and gut are intricately connected and respond to various stimuli. Stress-induced
brain-gut communication is implicated in the pathogenesis and relapse of gut disorders. The …

Diet, gut microbiota, and health: a review

L Zhang, H Tuoliken, J Li, H Gao - Food Science and Biotechnology, 2024 - Springer
The relationship between diet and human physical and mental health is highly
interconnected and has been significantly correlated with the occurrence of various …

[HTML][HTML] Bacterial peptidoglycan signalling in microglia: Activation by MDP via the NF-κB/MAPK pathway

J Spielbauer, EJ Glotfelty, H Sarlus, RA Harris… - Brain, Behavior, and …, 2024 - Elsevier
Bacterial peptidoglycan (PGN) fragments are commonly studied in the context of bacterial
infections. However, PGN fragments recently gained recognition as signalling molecules …

[HTML][HTML] Multiple neuronal populations control the eating behavior in Hydra and are responsive to microbial signals

C Giez, D Pinkle, Y Giencke, J Wittlieb, E Herbst… - Current Biology, 2023 - cell.com
Although recent studies indicate the impact of microbes on the central nervous systems and
behavior, it remains unclear how the relationship between the functionality of the nervous …

The oral microbiota and cardiometabolic health: A comprehensive review and emerging insights

Y Li, M Zhu, Y Liu, B Luo, J Cui, L Huang… - Frontiers in …, 2022 - frontiersin.org
There is mounting evidence demonstrating that oral dysbiosis causes periodontal disease
and promotes the development of cardiovascular disease. The advancement of omics …