[HTML][HTML] MiR-210 in exosomes derived from CAFs promotes non-small cell lung cancer migration and invasion through PTEN/PI3K/AKT pathway
F Yang, Y Yan, Y Yang, X Hong, M Wang, Z Yang… - Cellular signalling, 2020 - Elsevier
Abstract Objective Cancer-associated fibroblasts (CAFs) function as a crucial factor in tumor
progression by carrying exosomes to neighboring cells. This study was assigned to expound …
progression by carrying exosomes to neighboring cells. This study was assigned to expound …
[HTML][HTML] Translation initiation mediated by nuclear cap-binding protein complex
I Ryu, YK Kim - BMB reports, 2017 - ncbi.nlm.nih.gov
In mammals, cap-dependent translation of mRNAs is initiated by two distinct mechanisms:
cap-binding complex (CBC; a heterodimer of CBP80 and 20)-dependent translation (CT) …
cap-binding complex (CBC; a heterodimer of CBP80 and 20)-dependent translation (CT) …
[HTML][HTML] AKT constitutes a signal-promoted alternative exon-junction complex that regulates nonsense-mediated mRNA decay
H Cho, ET Abshire, MW Popp, C Pröschel, JL Schwartz… - Molecular cell, 2022 - cell.com
Despite a long appreciation for the role of nonsense-mediated mRNA decay (NMD) in
destroying faulty, disease-causing mRNAs and maintaining normal, physiologic mRNA …
destroying faulty, disease-causing mRNAs and maintaining normal, physiologic mRNA …
A role for AKT1 in nonsense-mediated mRNA decay
M Palma, C Leroy, S Salomé-Desnoulez… - Nucleic acids …, 2021 - academic.oup.com
Nonsense-mediated mRNA decay (NMD) is a highly regulated quality control mechanism
through which mRNAs harboring a premature termination codon are degraded. It is also a …
through which mRNAs harboring a premature termination codon are degraded. It is also a …
UPF1/SMG7-dependent microRNA-mediated gene regulation
The stability and quality of metazoan mRNAs are under microRNA (miRNA)-mediated and
nonsense-mediated control. Although UPF1, a core mediator of nonsense-mediated mRNA …
nonsense-mediated control. Although UPF1, a core mediator of nonsense-mediated mRNA …
AKT but not MYC promotes reactive oxygen species-mediated cell death in oxidative culture
D Zheng, JH Sussman, MP Jeon… - Journal of cell …, 2020 - journals.biologists.com
Oncogenes can create metabolic vulnerabilities in cancer cells. We tested how AKT (herein
referring to AKT1) and MYC affect the ability of cells to shift between respiration and …
referring to AKT1) and MYC affect the ability of cells to shift between respiration and …
Endoplasmic Reticulum Stress in Mice Increases Hepatic Expression of Genes Carrying a Premature Termination Codon via a Nutritional Status‐Independent GRP78 …
N Harada, M Okuyama, A Yoshikatsu… - Journal of Cellular …, 2017 - Wiley Online Library
Nonsense‐mediated mRNA decay (NMD) degrades mRNAs carrying a premature
termination codon (PTC) in eukaryotes. Cellular stresses, including endoplasmic reticulum …
termination codon (PTC) in eukaryotes. Cellular stresses, including endoplasmic reticulum …
Differential expression of novel MicroRNAs from developing fetal heart of Gallus gallus domesticus implies a role in cardiac development
Heart development is a complex process regulated by multi-layered genetic as well
epigenetic regulators many of which are still unknown. Besides their critical role during …
epigenetic regulators many of which are still unknown. Besides their critical role during …
L'implication et le rôle de la protéine kinase AKT1 dans le mécanisme de Nonsense-mediated mRNA decay (NMD)
M Palma - 2021 - theses.hal.science
La protéine AKT1, appelée aussi protéine kinase B ou PKB, est un composant central de la
voie de signalisation PI3K/AKT/mTOR qui représente une des voies majoritaires des …
voie de signalisation PI3K/AKT/mTOR qui représente une des voies majoritaires des …
[PDF][PDF] Der Einfluss von HIV-1 induzierten Veränderungen des PI3K/Akt Signalwegs auf das alternative Spleißen in T-Zellen
NN Diehl - 2016 - docserv.uni-duesseldorf.de
Zusammenfassung Die Beteiligung des PI3K/Akt Signalwegs an zahlreichen zellulären
Prozessen wie der Proliferation, dem Überleben sowie der Proteinbiosynthese, macht ihn …
Prozessen wie der Proliferation, dem Überleben sowie der Proteinbiosynthese, macht ihn …