Protein acylation: mechanisms, biological functions and therapeutic targets
S Shang, J Liu, F Hua - Signal Transduction and Targeted Therapy, 2022 - nature.com
Metabolic reprogramming is involved in the pathogenesis of not only cancers but also
neurodegenerative diseases, cardiovascular diseases, and infectious diseases. With the …
neurodegenerative diseases, cardiovascular diseases, and infectious diseases. With the …
Fibroblast growth factor receptors as treatment targets in clinical oncology
M Katoh - Nature reviews Clinical oncology, 2019 - nature.com
FGFRs are receptor tyrosine kinases with a role in several biological processes, such as the
regulation of development and tissue repair. However, alterations in FGFRs 1–4, such as …
regulation of development and tissue repair. However, alterations in FGFRs 1–4, such as …
A not-so-ancient grease history: click chemistry and protein lipid modifications
Protein lipid modification involves the attachment of hydrophobic groups to proteins via
ester, thioester, amide, or thioether linkages. In this review, the specific click chemical …
ester, thioester, amide, or thioether linkages. In this review, the specific click chemical …
Engineering extracellular vesicles to deliver CRISPR ribonucleoprotein for gene editing
JA Whitley, H Cai - Journal of Extracellular Vesicles, 2023 - Wiley Online Library
Clustered regularly interspaced palindromic repeats (CRISPR) is a gene editing tool with
tremendous therapeutic potential. Recently, ribonucleoprotein (RNP) complex‐based …
tremendous therapeutic potential. Recently, ribonucleoprotein (RNP) complex‐based …
Post-translational modifications that drive prostate cancer progression
I Samaržija - Biomolecules, 2021 - mdpi.com
While a protein primary structure is determined by genetic code, its specific functional form is
mostly achieved in a dynamic interplay that includes actions of many enzymes involved in …
mostly achieved in a dynamic interplay that includes actions of many enzymes involved in …
Long-chain acyl-CoA synthetase 4–mediated fatty acid metabolism sustains androgen receptor pathway–independent prostate cancer
Y Ma, X Zhang, OA Alsaidan, X Yang… - Molecular Cancer …, 2021 - AACR
Androgen deprivation therapy has led to elevated cases of androgen receptor (AR) pathway–
independent prostate cancer with dysregulated fatty acid metabolism. However, it is unclear …
independent prostate cancer with dysregulated fatty acid metabolism. However, it is unclear …
Regulation of FGF10 signaling in development and disease
J Watson, C Francavilla - Frontiers in Genetics, 2018 - frontiersin.org
Fibroblast Growth Factor 10 (FGF10) is a multifunctional mesenchymal-epithelial signaling
growth factor, which is essential for multi-organ development and tissue homeostasis in …
growth factor, which is essential for multi-organ development and tissue homeostasis in …
MiR-326: promising biomarker for cancer
YJ Pan, J Wan, CB Wang - Cancer Management and Research, 2019 - Taylor & Francis
MicroRNAs (miRNAs) are small non-coding and highly conserved RNAs that act in
biological processes including cell proliferation, invasion, apoptosis, metabolism, signal …
biological processes including cell proliferation, invasion, apoptosis, metabolism, signal …
Fibroblast growth factor 10 alleviates acute lung injury by inhibiting excessive autophagy via Nrf2
S Huang, Y Xue, W Chen, M Xue, L Miao… - Journal of …, 2023 - joe.bioscientifica.com
Acute lung injury (ALI) is associated with an increased incidence of respiratory diseases,
which are devastating clinical disorders with high global mortality and morbidity. Evidence …
which are devastating clinical disorders with high global mortality and morbidity. Evidence …
Comprehensive analysis of potential cellular communication networks in advanced osteosarcoma using single-cell RNA sequencing data
N Xu, X Wang, L Wang, Y Song, X Zheng… - Frontiers in Genetics, 2022 - frontiersin.org
Osteosarcoma (OS) is a common bone cancer in children and adolescents, and metastasis
and recurrence are the major causes of poor treatment outcomes. A better understanding of …
and recurrence are the major causes of poor treatment outcomes. A better understanding of …