Searching for drugs for Chagas disease, leishmaniasis and schistosomiasis: a review
Chagas disease, leishmaniasis and schistosomiasis are neglected diseases (NDs) and are
a considerable global challenge. Despite the huge number of people infected, NDs do not …
a considerable global challenge. Despite the huge number of people infected, NDs do not …
Application of nanotechnology in treatment of leishmaniasis: a review
Leishmaniasis is a neglected tropical disease caused by a protozoan species of the genus
Leishmania affecting mostly the developing countries. The disease with current mortality rate …
Leishmania affecting mostly the developing countries. The disease with current mortality rate …
[HTML][HTML] Exploring Leishmania secretory proteins to design B and T cell multi-epitope subunit vaccine using immunoinformatics approach
Visceral leishmaniasis (VL) is a fatal form of leishmaniasis which affects 70 countries,
worldwide. Increasing drug resistance, HIV co-infection, and poor health system require …
worldwide. Increasing drug resistance, HIV co-infection, and poor health system require …
[HTML][HTML] Recent advancement and development of chitin and chitosan-based nanocomposite for drug delivery: Critical approach to clinical research
A Ahmad, NM Mubarak, K Naseem, H Tabassum… - Arabian Journal of …, 2020 - Elsevier
This review depicts the exposure of chitin and chitosan base multifunctional nanomaterial
composites for promising applications in field of biomedical science structure, synthesis as …
composites for promising applications in field of biomedical science structure, synthesis as …
[HTML][HTML] A Screen against Leishmania Intracellular Amastigotes: Comparison to a Promastigote Screen and Identification of a Host Cell-Specific Hit
G De Muylder, KKH Ang, S Chen… - PLoS neglected …, 2011 - journals.plos.org
The ability to screen compounds in a high-throughput manner is essential in the process of
small molecule drug discovery. Critical to the success of screening strategies is the proper …
small molecule drug discovery. Critical to the success of screening strategies is the proper …
[HTML][HTML] Leishmaniasis vaccine: where are we today?
L Kedzierski - Journal of global infectious diseases, 2010 - journals.lww.com
Leishmaniasis is a disease that ranges in severity from skin lesions to serious disfigurement
and fatal systemic infection. WHO has classified the disease as emerging and uncontrolled …
and fatal systemic infection. WHO has classified the disease as emerging and uncontrolled …
Efficacy of biogenic selenium nanoparticles against Leishmania major: in vitro and in vivo studies
N Beheshti, S Soflaei, M Shakibaie, MH Yazdi… - Journal of Trace …, 2013 - Elsevier
Project: This study investigated the in vitro and in vivo effectiveness of biogenic selenium
nanoparticles (Se NPs), biosynthesized by Bacillus sp. MSh-1, against Leishmania major …
nanoparticles (Se NPs), biosynthesized by Bacillus sp. MSh-1, against Leishmania major …
From mouse to man: safety, immunogenicity and efficacy of a candidate leishmaniasis vaccine LEISH‐F3+ GLA‐SE
RN Coler, MS Duthie, KA Hofmeyer… - Clinical & …, 2015 - Wiley Online Library
Key antigens of Leishmania species identified in the context of host responses in
Leishmania‐exposed individuals from disease‐endemic areas were prioritized for the …
Leishmania‐exposed individuals from disease‐endemic areas were prioritized for the …
Repurposing as a strategy for the discovery of new anti-leishmanials: the-state-of-the-art
RL Charlton, B Rossi-Bergmann, PW Denny, PG Steel - Parasitology, 2018 - cambridge.org
Leishmaniasis is a vector-borne neglected tropical disease caused by protozoan parasites
of the genus Leishmania for which there is a paucity of effective viable non-toxic drugs …
of the genus Leishmania for which there is a paucity of effective viable non-toxic drugs …
Polyamine metabolism in Leishmania: from arginine to trypanothione
Polyamines (PAs) are essential metabolites in eukaryotes, participating in a variety of
proliferative processes, and in trypanosomatid protozoa play an additional role in the …
proliferative processes, and in trypanosomatid protozoa play an additional role in the …