Among various factors, such as an unhealthy diet or a sedentarity lifestyle, excessive
fructose consumption is known to favor nonalcoholic fatty liver disease (NAFLD), as fructose …

Insulin resistance (IR) is a condition which refers to individuals whose cells and tissues
become insensitive to the peptide hormone, insulin. Over the recent years, a wealth of data …

Diabetes mellitus (DM) is a growing health concern in society. Type 1 and type 2 DM are the
two main types of diabetes; both types are chronic diseases that affect glucose metabolism …

In this study, we aimed to investigate the effects of p-Coumaric acid (PCA) on cisplatin (CIS)-
induced hepatotoxicity and nephrotoxicity in Wistar adult rats for 24 h compared to untreated …

Liver fibrosis can progress to cirrhosis, which is considered a serious disease. The Child-
Pugh score and the model of end-stage liver disease score have been established to assess …

Blood contains powerful pH-buffering molecules such as hemoglobin (Hb) and albumin,
while interstitial fluids have little pH-buffering molecules. Thus, even under metabolic …

Background High fat or fructose induces non-alcoholic fatty liver disease (NAFLD)
accompanied of mitochondrial dysfunction and oxidative stress. Controversy remains about …

Hormone-sensitive lipase (HSL) is one of the three lipases in adipose tissue present during
periods of energy demand. HSL is tightly controlled by insulin regulation via the central and …

We hypothesized that a polyphenol‐rich extract from Vitis vinifera L. grape skin (GSE) may
exert beneficial effects on obesity and related metabolic disorders induced by a high‐fat diet …

Introduction Cysteamine, a powerful endogenous antioxidant, is produced mostly by the
vanin-1 with pantetheinase activity. With regard to glycemic, inflammatory, and redox factors …