Reward signals in the cerebellum: origins, targets, and functional implications
D Kostadinov, M Häusser - Neuron, 2022 - cell.com
The cerebellum has long been proposed to play a role in cognitive function, although this
has remained controversial. This idea has received renewed support with the recent …
has remained controversial. This idea has received renewed support with the recent …
Bidirectional learning in upbound and downbound microzones of the cerebellum
CI De Zeeuw - Nature Reviews Neuroscience, 2021 - nature.com
Over the past several decades, theories about cerebellar learning have evolved. A relatively
simple view that highlighted the contribution of one major form of heterosynaptic plasticity to …
simple view that highlighted the contribution of one major form of heterosynaptic plasticity to …
Predictive and reactive reward signals conveyed by climbing fiber inputs to cerebellar Purkinje cells
There is increasing evidence for a cerebellar contribution to cognitive processing, but the
specific input pathways conveying this information remain unclear. We probed the role of …
specific input pathways conveying this information remain unclear. We probed the role of …
Local synaptic inhibition mediates cerebellar granule cell pattern separation and enables learned sensorimotor associations
The cerebellar cortex has a key role in generating predictive sensorimotor associations. To
do so, the granule cell layer is thought to establish unique sensorimotor representations for …
do so, the granule cell layer is thought to establish unique sensorimotor representations for …
Cognitive model discovery via disentangled RNNs
Computational cognitive models are a fundamental tool in behavioral neuroscience. They
embody in software precise hypotheses about the cognitive mechanisms underlying a …
embody in software precise hypotheses about the cognitive mechanisms underlying a …
Cerebellum, predictions and errors
Making predictions and validating the predictions against actual sensory information is
thought to be one of the most fundamental functions of the nervous system. A growing body …
thought to be one of the most fundamental functions of the nervous system. A growing body …
Representational geometry of perceptual decisions in the monkey parietal cortex
Lateral intraparietal (LIP) neurons represent formation of perceptual decisions involving eye
movements. In circuit models for these decisions, neural ensembles that encode actions …
movements. In circuit models for these decisions, neural ensembles that encode actions …
[HTML][HTML] Brain-wide dynamics linking sensation to action during decision-making
Perceptual decisions rely on learned associations between sensory evidence and
appropriate actions, involving the filtering and integration of relevant inputs to prepare and …
appropriate actions, involving the filtering and integration of relevant inputs to prepare and …
Classical conditioning drives learned reward prediction signals in climbing fibers across the lateral cerebellum
Classical models of cerebellar learning posit that climbing fibers operate according to a
supervised learning rule to instruct changes in motor output by signaling the occurrence of …
supervised learning rule to instruct changes in motor output by signaling the occurrence of …
Homologous organization of cerebellar pathways to sensory, motor, and associative forebrain
Cerebellar outputs take polysynaptic routes to reach the rest of the brain, impeding
conventional tracing. Here, we quantify pathways between the cerebellum and forebrain by …
conventional tracing. Here, we quantify pathways between the cerebellum and forebrain by …