Watching proteins wiggle: mapping structures with two-dimensional infrared spectroscopy

A Ghosh, JS Ostrander, MT Zanni - Chemical reviews, 2017 - ACS Publications
Proteins exhibit structural fluctuations over decades of time scales. From the picosecond
side chain motions to aggregates that form over the course of minutes, characterizing protein …

How to get insight into amyloid structure and formation from infrared spectroscopy

SD Moran, MT Zanni - The journal of physical chemistry letters, 2014 - ACS Publications
There is an enormous amount of interest in the structures and formation mechanisms of
amyloid fibers. In this Perspective, we review the most common structural motifs of amyloid …

Real-time observation of organic cation reorientation in methylammonium lead iodide perovskites

AA Bakulin, O Selig, HJ Bakker… - The journal of …, 2015 - ACS Publications
The introduction of a mobile and polarized organic moiety as a cation in 3D lead-iodide
perovskites brings fascinating optoelectronic properties to these materials. The extent and …

Higher-order multidimensional and pump–probe spectroscopies

J Lüttig, S Mueller, P Malý, JJ Krich… - The journal of physical …, 2023 - ACS Publications
Transient absorption and coherent two-dimensional spectroscopy are widely established
methods for the investigation of ultrafast dynamics in quantum systems. Conventionally, they …

Ultrafast spectroscopy with photocurrent detection: watching excitonic optoelectronic systems at work

AA Bakulin, C Silva, E Vella - The journal of physical chemistry …, 2016 - ACS Publications
While ultrafast spectroscopy with photocurrent detection was almost unknown before 2012,
in the last 3 years, a number of research groups from different fields have independently …

Shot-to-shot 2D IR spectroscopy at 100 kHz using a Yb laser and custom-designed electronics

KM Farrell, JS Ostrander, AC Jones, BR Yakami… - Optics …, 2020 - opg.optica.org
The majority of 2D IR spectrometers operate at 1-10 kHz using Ti: Sapphire laser
technology. We report a 2D IR spectrometer designed around Yb: KGW laser technology …

Mode-selective vibrational modulation of charge transport in organic electronic devices

AA Bakulin, R Lovrincic, X Yu, O Selig… - Nature …, 2015 - nature.com
The soft character of organic materials leads to strong coupling between molecular, nuclear
and electronic dynamics. This coupling opens the way to influence charge transport in …

Transparent window 2D IR spectroscopy of proteins

MC Thielges - The Journal of chemical physics, 2021 - pubs.aip.org
Proteins are complex, heterogeneous macromolecules that exist as ensembles of
interconverting states on a complex energy landscape. A complete, molecular-level …

Two-dimensional sum-frequency generation reveals structure and dynamics of a surface-bound peptide

JE Laaser, DR Skoff, JJ Ho, Y Joo… - Journal of the …, 2014 - ACS Publications
Surface-bound polypeptides and proteins are increasingly used to functionalize inorganic
interfaces such as electrodes, but their structural characterization is exceedingly difficult with …

Spatially resolved two-dimensional infrared spectroscopy via wide-field microscopy

JS Ostrander, AL Serrano, A Ghosh, MT Zanni - ACS photonics, 2016 - ACS Publications
We report the first wide-field microscope for measuring two-dimensional infrared (2D IR)
spectroscopic images. We concurrently collect more than 16 000 2D IR spectra, made …