Cancer is a leading cause of death worldwide, particularly because of its high mortality rate
in patients who are diagnosed at late stages. Conventional biomarkers originating from …

Extrachromosomal circular DNA (eccDNA) is a double-stranded DNA molecule found in
various organisms, including humans. In the past few decades, the research on eccDNA has …

Extrachromosomal circular DNA was recently found to be particularly abundant in multiple
human cancer cells, although its frequency varies among different tumor types. Elevated …

Simple Summary Recently, within the research community, exosomes, transporters of
bioactive molecules involved in many signalling pathways and cell-to-cell communication …

Colorectal cancer (CRC) is one of the most common cancers worldwide, being the third most
diagnosed in the world and the second deadliest. Solid biopsy provides an essential guide …

Identifying molecular biomarkers promises to significantly improve the accuracy in cancer
diagnosis at its early stage. DNA nanomachines, which are designable and switchable …

The incidence and mortality of cancer are increasing each year. At present, the sensitivity
and specificity of the blood biomarkers that were used in clinical practice are low, which …

RASSF1A, one of the eight isoforms of the RASSF1 gene, is a tumor suppressor gene that
influences tumor initiation and development. In cancer, RASSF1A is frequently inactivated …

Globally, non-small cell lung cancer (NSCLC) is the leading cause of cancer deaths. Despite
advancements in chemotherapy and targeted therapies, the 5-year survival rate has …

There exist many different human cancers, but regardless of the cancer type, an early
diagnosis is a necessary condition for further optimal outcomes from the disease. Therefore …