Past, present and future of latent autoimmune diabetes in adults
Latent autoimmune diabetes in adults (LADA) is the most common form of autoimmune
diabetes diagnosed in adults. Similar to type 1 diabetes, the prevalence of LADA is impacted …
diabetes diagnosed in adults. Similar to type 1 diabetes, the prevalence of LADA is impacted …
What has zinc transporter 8 autoimmunity taught us about type 1 diabetes?
CL Williams, AE Long - Diabetologia, 2019 - Springer
Abstract Zinc transporter 8 (ZnT8), a protein highly specific to pancreatic insulin-producing
beta cells, is vital for the biosynthesis and secretion of insulin. ZnT8 autoantibodies (ZnT8A) …
beta cells, is vital for the biosynthesis and secretion of insulin. ZnT8 autoantibodies (ZnT8A) …
Children at onset of type 1 diabetes show altered N-glycosylation of plasma proteins and IgG
Aims/hypothesis Individual variation in plasma N-glycosylation has mainly been studied in
the context of diabetes complications, and its role in type 1 diabetes onset is largely …
the context of diabetes complications, and its role in type 1 diabetes onset is largely …
Integrated glycomics and genetics analyses reveal a potential role for N-glycosylation of plasma proteins and IgGs, as well as the complement system, in the …
Aims/hypothesis We previously demonstrated that N-glycosylation of plasma proteins and
IgGs is different in children with recent-onset type 1 diabetes compared with their healthy …
IgGs is different in children with recent-onset type 1 diabetes compared with their healthy …
Elevated cathepsin S serum levels in new-onset type 1 diabetes and autoantibody-positive siblings
C Frørup, MH Jensen, M Haupt-Jorgensen… - Diabetes, 2024 - Am Diabetes Assoc
Accumulating data suggest a role for the lysosomal protease cathepsin S (CTSS) in type 1
diabetes. Circulating CTSS is increased in type 1 diabetes; however, whether CTSS has …
diabetes. Circulating CTSS is increased in type 1 diabetes; however, whether CTSS has …
Genetic Variants Associated with Neuropeptide Y Autoantibody Levels in Newly Diagnosed Individuals with Type 1 Diabetes
SJ Mansachs, SO Villumsen, J Johannesen, A Lind… - Genes, 2022 - mdpi.com
(1) Autoantibodies to the leucine variant of neuropeptide Y (NPY-LA) have been found in
individuals with type 1 diabetes (T1D). We investigated the association between the levels of …
individuals with type 1 diabetes (T1D). We investigated the association between the levels of …
25‐Hydroxyvitamin D, Autoantigenic and Total Antibody Concentrations: Results from a Danish Case–control Study of Newly Diagnosed Patients with Childhood Type …
SU Thorsen, CB Pipper, J Johannesen… - Scandinavian …, 2018 - Wiley Online Library
B cells have recently entered the stage as an important accessory player in type 1 diabetes
(T1D) etiopathogenesis. Experimental studies suggest regulatory functions of vitamin D on B …
(T1D) etiopathogenesis. Experimental studies suggest regulatory functions of vitamin D on B …
[图书][B] Improving diagnosis of adult-onset diabetes using islet autoantibodies
SL Grace - 2023 - search.proquest.com
The diagnosis of diabetes type in adulthood can be difficult due to overlapping phenotypes
and lack of clear classification guidelines. Type 1 and type 2 diabetes have very different …
and lack of clear classification guidelines. Type 1 and type 2 diabetes have very different …