Matrix metalloproteinases: from molecular mechanisms to physiology, pathophysiology, and pharmacology

LGN de Almeida, H Thode, Y Eslambolchi… - Pharmacological …, 2022 - ASPET
The first matrix metalloproteinase (MMP) was discovered in 1962 from the tail of a tadpole by
its ability to degrade collagen. As their name suggests, matrix metalloproteinases are …

[HTML][HTML] Menstruation: science and society

HOD Critchley, E Babayev, SE Bulun, S Clark… - American journal of …, 2020 - Elsevier
Women's health concerns are generally underrepresented in basic and translational
research, but reproductive health in particular has been hampered by a lack of …

Modular combination of proteolysis-responsive transcription and spherical nucleic acids for smartphone-based colorimetric detection of protease biomarkers

F Liu, R Chen, W Song, L Li, C Lei, Z Nie - Analytical Chemistry, 2021 - ACS Publications
Sensitive and facile detection of biomarkers is essential for early diagnosis and treatment of
diseases. To this end, we here proposed a colorimetric protease assay by the modular …

Ligand‐directed modification of active matrix metalloproteases: activity‐based probes with no photolabile group

M Kaminska, P Bruyat, C Malgorn… - Angewandte …, 2021 - Wiley Online Library
Activity‐based probes enable discrimination between the active enzyme and its inactive or
inactivated counterparts. Since metalloproteases catalysis is non‐covalent, activity‐based …

A New Affinity-Based Probe to Profile MMP Active Forms

C Malgorn, F Becher, P Bruyat… - Proteases and Cancer …, 2023 - Springer
A new generation of affinity-based probes (A f BPs) has been developed to label and identity
matrix metalloproteinases (MMPs) under their active form in complex proteomes. First, the …

Direct monitoring of protease activity using an integrated microchip coated with multilayered fluorogenic nanofilms

D Yu, Y Chen, CC Ahrens, Y Wang, Z Ding, HT Lim… - Analyst, 2020 - pubs.rsc.org
Proteases play an essential role in the four sequential but overlapping phases of wound
healing: hemostasis, inflammation, proliferation, and remodeling. In chronic wounds …

[PDF][PDF] Expert Review ajog. org

HOD Critchley, E Babayev, SE Bulun, S Clark… - academia.edu
Women's health concerns are generally underrepresented in basic and translational
research, but reproductive health in particular has been hampered by a lack of …