Recognizing the importance of childhood maltreatment as a critical factor in psychiatric diagnoses, treatment, research, prevention, and education
MH Teicher, JB Gordon, CB Nemeroff - Molecular psychiatry, 2022 - nature.com
Childhood maltreatment is the most important preventable risk factor for psychiatric
disorders. Maltreated individuals typically develop psychiatric disorders at an earlier age …
disorders. Maltreated individuals typically develop psychiatric disorders at an earlier age …
Childhood adversity and neural development: A systematic review
KA McLaughlin, D Weissman… - Annual review of …, 2019 - annualreviews.org
An extensive literature on childhood adversity and neurodevelopment has emerged over the
past decade. We evaluate two conceptual models of adversity and neurodevelopment—the …
past decade. We evaluate two conceptual models of adversity and neurodevelopment—the …
The devastating clinical consequences of child abuse and neglect: increased disease vulnerability and poor treatment response in mood disorders
ETC Lippard, CB Nemeroff - American journal of psychiatry, 2023 - psychiatryonline.org
A large body of evidence has demonstrated that exposure to childhood maltreatment at any
stage of development can have long-lasting consequences. It is associated with a marked …
stage of development can have long-lasting consequences. It is associated with a marked …
[HTML][HTML] Canalization and plasticity in psychopathology
RL Carhart-Harris, S Chandaria, DE Erritzoe… - …, 2023 - Elsevier
This theoretical article revives a classical bridging construct, canalization, to describe a new
model of a general factor of psychopathology. To achieve this, we have distinguished …
model of a general factor of psychopathology. To achieve this, we have distinguished …
Developmental trajectories of early life stress and trauma: a narrative review on neurobiological aspects beyond stress system dysregulation
Early life stressors display a high universal prevalence and constitute a major public health
problem. Prolonged psychoneurobiological alterations as sequelae of early life stress (ELS) …
problem. Prolonged psychoneurobiological alterations as sequelae of early life stress (ELS) …
The effects of childhood maltreatment on brain structure, function and connectivity
MH Teicher, JA Samson, CM Anderson… - Nature reviews …, 2016 - nature.com
Maltreatment-related childhood adversity is the leading preventable risk factor for mental
illness and substance abuse. Although the association between maltreatment and …
illness and substance abuse. Although the association between maltreatment and …
Biological aging in childhood and adolescence following experiences of threat and deprivation: A systematic review and meta-analysis.
Life history theory argues that exposure to early life adversity (ELA) accelerates
development, although existing evidence for this varies. We present a meta-analysis and …
development, although existing evidence for this varies. We present a meta-analysis and …
Annual research review: enduring neurobiological effects of childhood abuse and neglect
MH Teicher, JA Samson - Journal of child psychology and …, 2016 - Wiley Online Library
Background Childhood maltreatment is the most important preventable cause of
psychopathology accounting for about 45% of the population attributable risk for childhood …
psychopathology accounting for about 45% of the population attributable risk for childhood …
Paradise lost: the neurobiological and clinical consequences of child abuse and neglect
CB Nemeroff - Neuron, 2016 - cell.com
In the past two decades, much evidence has accumulated unequivocally demonstrating that
child abuse and neglect is associated with a marked increase in risk for major psychiatric …
child abuse and neglect is associated with a marked increase in risk for major psychiatric …
Childhood adversity and neural development: Deprivation and threat as distinct dimensions of early experience
A growing body of research has examined the impact of childhood adversity on neural
structure and function. Advances in our understanding of the neurodevelopmental …
structure and function. Advances in our understanding of the neurodevelopmental …