Alzheimer's disease (AD) is a neurodegenerative disorder, most cases of which lack a clear
causative event. This has made the disease difficult to characterize and, thus, diagnose …

Traumatic brain injury (TBI) is one of the most common diseases in the central nervous
system (CNS) with high mortality and morbidity. Patients with TBI usually suffer many …

APOE4 is the greatest genetic risk factor for late-onset Alzheimer's disease (AD), increasing
the risk of developing the disease by 3-fold in the 14% of the population that are carriers …

Abstract Background Alzheimer's Disease (AD) is a neurodegenerative disorder influenced
by aging and genetic risk factors. The inheritance of APOE ε4 and variants of Triggering …

Repeated head impact exposure can cause memory and behavioral impairments. Here, we
report that exposure to non-damaging, but high frequency, head impacts can alter brain …

Background The application of advanced sequencing technologies and improved mass-
spectrometry platforms revealed significant changes in gene expression and lipids in …

Traumatic brain injury (TBI) is an unfortunately common event in military life. The conflicts in
Iraq and Afghanistan have increased public awareness of TBI in the military. Certain injury …

Background Complex changes in the brain microenvironment following traumatic brain
injury (TBI) can cause neurological impairments for which there are few efficacious …

The APOE gene encoding the Apolipoprotein E protein is the single most significant genetic
risk factor for late‐onset Alzheimer's disease. The APOE4 genotype confers a significantly …

Mild traumatic brain injury (mTBI) results in broad neurological symptoms and an increased
risk of being diagnosed with a neurodegenerative disease later in life. While the immediate …