Bullous pemphigoid: trigger and predisposing factors

F Moro, L Fania, JLM Sinagra, A Salemme, G Di Zenzo - Biomolecules, 2020 - mdpi.com
Bullous pemphigoid (BP) is the most frequent autoimmune subepidermal blistering disease
provoked by autoantibodies directed against two hemidesmosomal proteins: BP180 and …

Dipeptidyl peptidase-4 inhibitor-associated bullous pemphigoid

K Tasanen, O Varpuluoma, W Nishie - Frontiers in immunology, 2019 - frontiersin.org
Bullous pemphigoid (BP) is an organ-specific autoantibody-mediated blistering skin disease
that mainly affects the elderly. Typical clinical features include the widespread blisters, often …

Association of dipeptidyl peptidase 4 inhibitor use with risk of bullous pemphigoid in patients with diabetes

SG Lee, HJ Lee, MS Yoon, DH Kim - JAMA dermatology, 2019 - jamanetwork.com
Importance Recent studies suggest that dipeptidyl peptidase 4 (DPP-4) inhibitors are
associated with an increased risk of developing bullous pemphigoid (BP). Population-based …

Higher frequency of dipeptidyl peptidase-4 inhibitor intake in bullous pemphigoid patients than in the French general population

M Plaquevent, F Tétart, L Fardet… - Journal of Investigative …, 2019 - Elsevier
Dipeptidyl peptidase-4 inhibitors have been suspected to induce bullous pemphigoid (BP).
The objective of this study was to compare the observed frequency of gliptin intake in a large …

Bullous pemphigoid in diabetic patients treated by gliptins: the other side of the coin

K Chouchane, G Di Zenzo, D Pitocco… - Journal of Translational …, 2021 - Springer
Bullous pemphigoid (BP) is the most common autoimmune bullous skin disease that affects
primarily patients older than 60 years. The majority of BP cases are spontaneous, but BP …

The role of dipeptidyl peptidase‐4 in cutaneous disease

PM Patel, VA Jones, K Kridin… - Experimental …, 2021 - Wiley Online Library
Abstract Dipeptidyl peptidase‐4 (DPP4) is a multifunctional, transmembrane glycoprotein
present on the cell surface of various tissues. It is present in multiple molecular forms …

Gliptin-associated bullous pemphigoid and the expression of dipeptidyl peptidase-4/CD26 in bullous pemphigoid

O Lindgren, O Varpuluoma, J Tuusa, J Ilonen, L Huilaja… - 2019 - oulurepo.oulu.fi
Abstract Dipeptidyl peptidase-4 inhibitors (DPP-4i or gliptins) increase the risk of developing
bullous pemphigoid (BP). To clarify, whether gliptin-associated BP has special features, we …

Gliptin accountability in mucous membrane pemphigoid induction in 24 out of 313 patients

O Gaudin, V Seta, M Alexandre, G Bohelay… - Frontiers in …, 2018 - frontiersin.org
Mucous membrane pemphigoids (MMPs) and bullous pemphigoid (BP) are autoimmune
bullous diseases that share physiopathological features: both can result from autoantibodies …

Dipeptidyl peptidase‐4 inhibitor treatment and the risk of bullous pemphigoid and skin‐related adverse events: a systematic review and meta‐analysis of randomized …

W Yang, X Cai, S Zhang, X Han… - … Metabolism Research and …, 2021 - Wiley Online Library
Aims This meta‐analysis aimed to evaluate the risk of developing bullous pemphigoid (BP)
and other skin‐related adverse events (AEs) in patients with type 2 diabetes (T2DM) …

[HTML][HTML] Dipeptidyl peptidase-4 inhibitor-induced autoimmune diseases: Current evidence

A Roy, J Sahoo, N Narayanan, C Merugu… - World Journal of …, 2021 - ncbi.nlm.nih.gov
Abstract Dipeptidyl peptidase-4 inhibitors (DPP-4i) have an important place in the
management of type 2 diabetes. The DPP-4 enzyme is ubiquitously distributed throughout …