Prostaglandin E2 and cancer: insight into tumor progression and immunity

F Finetti, C Travelli, J Ercoli, G Colombo, E Buoso… - Biology, 2020 - mdpi.com
Simple Summary Inflammation is assessed as a hallmark of cancer and it is now widely
recognized that there exists a direct causal link between inflammation and tumors. Among …

The platelet lifeline to cancer: challenges and opportunities

M Haemmerle, RL Stone, DG Menter… - Cancer cell, 2018 - cell.com
Besides their function in limiting blood loss and promoting wound healing, experimental
evidence has highlighted platelets as active players in all steps of tumorigenesis including …

[HTML][HTML] Perioperative events influence cancer recurrence risk after surgery

JG Hiller, NJ Perry, G Poulogiannis, B Riedel… - Nature reviews Clinical …, 2018 - nature.com
Surgery is a mainstay treatment for patients with solid tumours. However, despite surgical
resection with a curative intent and numerous advances in the effectiveness of (neo) …

A framework for the development of effective anti-metastatic agents

RL Anderson, T Balasas, J Callaghan… - Nature Reviews …, 2019 - nature.com
Most cancer-related deaths are a result of metastasis, and thus the importance of this
process as a target of therapy cannot be understated. By asking 'how can we effectively treat …

Chemoprevention of colorectal cancer

BW Katona, JM Weiss - Gastroenterology, 2020 - Elsevier
Although colorectal cancer (CRC) screening has reduced the incidence of and mortality from
CRC, chemoprevention strategies have the potential to further reduce CRC incidence and …

Crosstalk between DNA damage and inflammation in the multiple steps of carcinogenesis

S Kawanishi, S Ohnishi, N Ma, Y Hiraku… - International journal of …, 2017 - mdpi.com
Inflammation can be induced by chronic infection, inflammatory diseases and
physicochemical factors. Chronic inflammation is estimated to contribute to approximately …

Colon cancer therapy by focusing on colon cancer stem cells and their tumor microenvironment

Z Jahanafrooz, J Mosafer, M Akbari… - Journal of cellular …, 2020 - Wiley Online Library
Despite many advances and optimization in colon cancer treatment, tumor recurrence and
metastases make the development of new therapies necessary. Colon cancer stem cells …

[HTML][HTML] Platelet-derived extracellular vesicles: an emerging therapeutic approach

SC Tao, SC Guo, CQ Zhang - International journal of biological …, 2017 - ncbi.nlm.nih.gov
Extracellular vesicles (EVs) are a newly-discovered way by which cells communicate with
their neighbors, as well as transporting cargos which once were considered to be limited by …

[HTML][HTML] Pharmacological management of cancer pain: Novel therapeutics

CG Virgen, N Kelkar, A Tran, CM Rosa… - Biomedicine & …, 2022 - Elsevier
Patients diagnosed with cancer often experience pain during their treatment course, making
it difficult to care for themselves and continue with their activities of daily living. When cancer …

Targeting lipid peroxidation for cancer treatment

SM Clemente, OH Martínez-Costa, M Monsalve… - Molecules, 2020 - mdpi.com
Cancer is one of the highest prevalent diseases in humans. The chances of surviving cancer
and its prognosis are very dependent on the affected tissue, body location, and stage at …