The S100 family of proteins contains 25 known members that share a high degree of
sequence and structural similarity. However, only a limited number of family members have …

The S100 proteins, a family of calcium-binding cytosolic proteins, have a broad range of
intracellular and extracellular functions through regulating calcium balance, cell apoptosis …

The S100 protein family consists of 24 members functionally distributed into three main
subgroups: those that only exert intracellular regulatory effects, those with intracellular and …

Damage-associated molecular pattern (DAMP) molecules have been introduced as
important proinflammatory factors of innate immunity. One example known for many years to …

Zn2+ ions are essential in many physiological processes, including enzyme catalysis,
protein structural stabilization, and the regulation of many proteins. The affinities of proteins …

The S100 family of EF-hand calcium (Ca 2+)-binding proteins is essential for a wide range of
cellular functions. During infection, certain S100 proteins act as damage-associated …

This review focuses on new aspects of extracellular roles of the calgranulins. S100A8,
S100A9 and S100A12 are constitutively expressed in neutrophils and induced in several …

Metastasis is the leading cause of cancer-related death and directly associates with cancer
progression, resistance to anticancer therapy, and poor patient survival. Current efforts …

The transition from benign tumor growth to malignancy is manifested by the ability of tumor
cells to traverse tissue barriers and invade surrounding tissues. The traversal of basement …

Myeloid‐derived suppressor cells (MDSC) are a heterogeneous population of cells that
negatively regulate the immune response during tumour progression, inflammation and …