Advances in label-free detections for nanofluidic analytical devices

THH Le, H Shimizu, K Morikawa - Micromachines, 2020 - mdpi.com
Nanofluidics, a discipline of science and engineering of fluids confined to structures at the 1–
1000 nm scale, has experienced significant growth over the past decade. Nanofluidics have …

An inert 3D emulsification device for individual precipitation and concentration of amorphous drug nanoparticles

T Lorenz, S Bojko, H Bunjes, A Dietzel - Lab on a Chip, 2018 - pubs.rsc.org
Nanosizing increases the specific surface of drug particles, leading to faster dissolution
inside the organism and improving the bioavailability of poorly water-soluble drugs. A novel …

Optically monitored segmented flow for controlled ultra-fast mixing and nanoparticle precipitation

P Erfle, J Riewe, H Bunjes, A Dietzel - Microfluidics and Nanofluidics, 2017 - Springer
Nanoparticles of drugs or colloidal carrier systems are capable of providing substantial
advantages for drug bioavailability, but manufacturing nanoparticulate drugs or drug carriers …

Resonant dielectric metagratings for response intensified optical sensing

RA Aoni, S Manjunath, BI Karawdeniya… - Advanced Functional …, 2022 - Wiley Online Library
The development of nanoscale optical sensors is desirable for a broad range of
applications, including wearable medical‐diagnostics, biochemical detection, and …

Nonfluorescent Molecule Detection in 102 nm Nanofluidic Channels by Photothermal Optical Diffraction

Y Tsuyama, K Mawatari - Analytical chemistry, 2019 - ACS Publications
Integrating analytical systems in 101–103 nm spaces provides ultrasensitive analytical
devices at the single cell and the single molecule levels due to the ultrasmall space, and …

Demonstration of a label-free and low-cost optical cavity-based biosensor using streptavidin and C-reactive protein

D Rho, S Kim - Biosensors, 2020 - mdpi.com
An optical cavity-based biosensor (OCB) has been developed for point-of-care (POC)
applications. This label-free biosensor employs low-cost components and simple fabrication …

Ultrasensitive Refractometry via Supercritical Angle Fluorescence

B Ferdman, LE Weiss, O Alalouf, Y Haimovich… - ACS …, 2018 - ACS Publications
Refractometry, namely, the measurement of refractive index (RI), provides information about
various sample properties such as concentrations and molecular structure. One physical …

Optofluidic refractive index sensor based on asymmetric diffraction

X Tu, Y Luo, T Huang, J Gan, C Song - Optics Express, 2019 - opg.optica.org
A novel optofluidic refracrtive index (RI) sensor was proposed based on asymmetric
Fraunhofer diffraction. In-plane optofluidic lens, light source, slit, diffraction pattern …

Cross-Flow Filtration of Escherichia coli at a Nanofluidic Gap for Fast Immobilization and Antibiotic Susceptibility Testing

JF Busche, S Möller, M Stehr, A Dietzel - Micromachines, 2019 - mdpi.com
Infections with antimicrobial-resistant (AMR) bacteria are globally on the rise. In the future,
multi-resistant infections will become one of the major problems in global health care. In …

[HTML][HTML] Biosensing based on optimized asymmetric optofluidic nanochannel gratings

F Purr, RD Lowe, M Stehr, M Singh, TP Burg… - Micro and Nano …, 2020 - Elsevier
Interferometric biosensing offers the potential of label-free detection with very high
sensitivities. In our optofluidic grating detector the accumulation of biological target …