Per-Arnt-Sim (PAS) domains occur in proteins from all kingdoms of life. In the bacterial
kingdom, PAS domains are commonly positioned at the amino terminus of signaling proteins …

LOV (light, oxygen or voltage) domains are protein photosensors that are conserved in
bacteria, archaea, plants and fungi, and detect blue light via a flavin cofactor. LOV domains …

Ascorbate (vitamin C) is an essential antioxidant in fresh fruits and vegetables. To gain
insight into the regulation of ascorbate metabolism in plants, we studied mutant tomato …

Light–oxygen–voltage sensitive (LOV) flavoproteins are ubiquitous photoreceptors that
mediate responses to environmental cues. Photosensory inputs are transduced into …

Light is an essential source of energy for life on Earth and is one of the most important
signals that organisms use to obtain information from the surrounding environment, on land …

Photoreceptor flavoproteins of the LOV, BLUF, and cryptochrome families are ubiquitous
among the three domains of life and are configured as UVA/blue-light systems not only in …

Signal perception is a key function in regulating biological activities and adapting to
changing environments. Per-Arnt-Sim (PAS) domains are ubiquitous sensors found in …

Highlights•Flavin-binding LOV domains have been engineered as green fluorescent
reporters.•Several LOV-based FPs are available with different photophysical …

The widespread bacterial second messenger c-di-GMP is responsible for regulating many
important physiological functions such as biofilm formation, motility, cell differentiation, and …

Virtually all organisms exposed to light are capable of sensing this environmental signal. In
recent years the photoreceptors that mediate the ability of fungi to “see” have been identified …