Organoborons have emerged as versatile building blocks in organic synthesis to achieve
molecular diversity and as carboxylic acid bioisosteres with broad applicability in drug …

In the past few decades, polymeric nanocarriers have been recognized as promising tools
and have gained attention from researchers for their potential to efficiently deliver bioactive …

Therapeutic options for the highly pathogenic human coronavirus (HCoV) infections are
urgently needed. Anticoronavirus therapy is however challenging, as coronaviruses are …

Light is of essential importance to the universe and humankind. Light has been, and
continues to be, one of the most fundamental and indispensable elements to life and society …

The world is made up of fundamental elements, ions and molecules that continuously
interact with each other through a series of chemical reactions. Thus, it is important to have a …

A conceptually new “light-up” biosensor with a high specificity for d-glucose (Glu) in
aqueous media has been developed. The emission from a tetraphenylethene (TPE)-cored …

In 2003, bortezomib, a first-in-class therapeutic, gained approval from the US Federal Drug
Administration for the treatment of relapsed multiple myeloma and mantle cell lymphoma …

Many successful stories in enzyme engineering are based on the creation of randomized
diversity in large mutant libraries, containing millions to billions of enzyme variants. Methods …

Structurally, boronic acids are trivalent boron-containing organic compounds that possess
one alkyl substituent (ie, a C–B bond) and two hydroxyl groups to fill the remaining valences …

Carbohydrates are known to mediate a large number of biological and pathological events.
Small and macromolecules capable of carbohydrate recognition have great potentials as …